Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 6/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | HTR1B | P28222 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | GSK3B | P49841 | 2/20 | 0.43 |
| ▸ | POLM | Q9NP87 | 2/20 | 0.41 |
| ▸ | POLK | Q9UBT6 | 2/20 | 0.41 |
| ▸ | POLL | Q9UGP5 | 2/20 | 0.41 |
| ▸ | POLH | Q9Y253 | 2/20 | 0.41 |
| ▸ | TOP2A | P11388 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1122032 | 1.00 | ALOX15 (0.48) | ALOX15HTR1AHTR1BNR4A2HTR2A | |
| SCHEMBL9300226 | 0.91 | NR4A2 (0.51) | ALOX15NR4A2HTR2AGSK3BGPR84 | |
| SCHEMBL28002128 | 0.90 | HTR1A (0.52) | ALOX15HTR1AHTR1BNR4A2HTR2A | |
| SCHEMBL1121872 | 0.85 | HTR2A (0.48) | ALOX15HTR1AHTR1BHTR2AGSK3B | |
| SCHEMBL29000165 | 0.82 | SLC22A6 (0.58) | HTR1AHTR1BHTR2APOLMPOLK | |
| SCHEMBL1121806 | 0.82 | SLC22A6 (0.58) | HTR1AHTR1BHTR2APOLMPOLK | |
| SCHEMBL4558873 | 0.82 | SLC22A6 (0.58) | HTR1AHTR1BHTR2APOLMPOLK | |
| SCHEMBL1121837 | 0.81 | HTR1A (0.43) | ALOX15HTR1AHTR1BHTR2AGSK3B | |
| SCHEMBL28258881 | 0.81 | SLC22A6 (0.60) | HTR1AHTR1BHTR2APOLMPOLK | |
| SCHEMBL17242053 | 0.81 | NR4A2 (0.51) | NR4A2HTR2AGPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1334204-B1 | METHOD AND MEDIUM FOR DETECTING/IDENTIFYING MICRO-ORGANISMS WITH ESTERASE ACTIVITY | BIO MERIEUX (FR) | 2007-10-31 | — | — | EP | disclosed |
| US-7235379-B2 | Method and medium for the detection/identification of microorgranisms with esterase activity | BIO MERIEUX (FR) | 2007-06-26 | — | — | US | disclosed |
| US-7217536-B2 | Medium and method for detecting/identifying microorganisms | BIO MERIEUX (FR) | 2007-05-15 | — | — | US | disclosed |
| US-20050014215-A1 | Method and medium for the detecting/identifying microorganisms with esterase and/or r osidase and/or peptidase and/or sulfatase and/or phosphatase activity | BIO MERIEUX (FR) | 2005-01-20 | — | — | US | disclosed |
| US-20040048326-A1 | Method and medium for etecting/identifying micro-orgranisms with esterase activity | BIO MERIEUX (FR) | 2004-03-11 | — | — | US | disclosed |