SCHEMBL5275474

SCHEMBL5275474

Cc1nnnn1C(=O)n1cnnn1

nearest known ligand 0.36

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KCNJ1 P48048 8/20 0.36
NOTUM Q6P988 1/20 0.34
LMNA P02545 2/20 0.33
MAPK1 P28482 1/20 0.33
GAA P10253 1/20 0.32
MAPT P10636 1/20 0.32
TSHR P16473 1/20 0.32
KMT2A Q03164 1/20 0.32
ALDH1A1 P00352 2/20 0.31
HMGCR P04035 1/20 0.31
KDM4E B2RXH2 1/20 0.31
HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5275093 0.81 HMGCR (0.31) KCNJ1HMGCR
SCHEMBL5277085 0.81 KCNJ1 (0.30) KCNJ1
SCHEMBL5280320 0.81 KCNJ1 (0.30) KCNJ1NOTUM
SCHEMBL5282490 0.80 KCNJ1 (0.31) KCNJ1
SCHEMBL5277314 0.80 DAGLA (0.34) KCNJ1ALDH1A1
SCHEMBL5276975 0.80 NOTUM (0.32) KCNJ1NOTUMALDH1A1
SCHEMBL5275312 0.78 MGLL (0.44) LMNATSHRKMT2AALDH1A1HPGD
SCHEMBL5274284 0.77
SCHEMBL5279141 0.77
SCHEMBL5276277 0.77 DAGLA (0.35) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1859783-A1 Brightening and/or colouring agent comprising N, N'-carbonyldiazoles and/or analagogues thereof Henkel Kommanditgesellschaft auf Aktien (DE) 2007-11-28 EP disclosed