⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL867085 | 1.00 | CYP1A2 (0.40) | — | |
| SCHEMBL866288 | 1.00 | CYP1A2 (0.40) | — | |
| SCHEMBL5143 | 1.00 | CYP1A2 (0.40) | — | |
| SCHEMBL4325 | 1.00 | CYP1A2 (0.40) | — | |
| SCHEMBL5241 | 0.97 | — | — | |
| SCHEMBL5481 | 0.91 | — | — | |
| SCHEMBL5172 | 0.84 | — | — | |
| SCHEMBL818572 | 0.78 | NOS2 (0.46) | — | |
| SCHEMBL818573 | 0.78 | NOS2 (0.46) | — | |
| SCHEMBL10597539 | 0.78 | NOS2 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 379 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104974369-B | A kind of preparation method of polypropylene foaming beads | 中国石油化工股份有限公司 | 2018-01-23 | — | — | CN | claimed |
| CN-101203504-B | Antimicrobial agents | RANBAXY LAB LTD | 2012-11-14 | — | — | CN | claimed |
| CN-102369188-A | Substituted nicotinamides as KCNQ2/3 modulators | GRUENENTHAL GMBH | 2012-03-07 | — | — | CN | claimed |
| CN-102348692-A | Substituted 2-mercaptoquinoline-3-carboxamides as kcnq2/3 modulators | GRUENENTHAL GMBH | 2012-02-08 | — | — | CN | claimed |
| EP-1569911-B1 | INDAZOLE DERIVATIVES AS CRF ANTAGONISTS | HOFFMANN LA ROCHE (CH) | 2008-07-02 | — | — | EP | claimed |
| CN-101203504-A | Antimicrobial agents | RANBAXY LAB LTD (IN) | 2008-06-18 | — | — | CN | claimed |
| CN-1891220-A | Use of 2-amino-3-alkylpyrimidinone derivatives for producing medicaments | SANOFI SYNTHELABO (FR) | 2007-01-10 | — | — | CN | claimed |
| CN-1247567-C | 2-amino-3-alkylpyrimidinone derivatives as GSK3 beta inhibitors | SANOFI AVENTIS (FR) | 2006-03-29 | — | — | CN | claimed |
| EP-0951466-A2 | CYCLOALKYL, LACTAM, LACTONE AND RELATED COMPOUNDS, PHARMACEUTICAL COMPOSITIONS COMPRISING SAME, AND METHODS FOR INHIBITING BETA-AMYLOID PEPTIDE RELEASE AND/OR ITS SYNTHESIS BY USE OF SUCH COMPOUNDS | Elan Pharmaceuticals, Inc. (US) | 1999-10-27 | — | — | EP | claimed |
| WO-1998028268-A2 | CYCLOALKYL, LACTAM, LACTONE AND RELATED COMPOUNDS AS β-AMYLOID PEPTIDE RELEASE INHIBITORS | ELAN PHARMACEUTICALS, INC. (US) | 1998-07-02 | — | — | WO | claimed |
| EP-0284952-A2 | Substituted propylamines | BAYER AG (DE) | 1988-10-05 | — | — | EP | claimed |
| US-4178367-A | Prostaglandin I2 analogues | ONO PHARMACEUTICAL CO. LTD. (JP) | 1979-12-11 | — | — | US | claimed |
| EP-4347597-A1 | PYRAZOLO[1,5-A]PYRIMIDINE COMPOUND FOR THE TREATMENT OF DERMAL DISORDERS | Otsuka Pharmaceutical Co., Ltd. (JP) | 2024-04-10 | — | — | EP | disclosed |
| US-20240016149-A1 | HERBICIDAL MALONAMIDES | BASF SE (DE) | 2024-01-18 | — | — | US | disclosed |
| CN-117377674-A | Pyrazolo [1,5-a ] pyrimidine compounds for the treatment of dermatological disorders | 大塚制药株式会社 | 2024-01-09 | — | — | CN | disclosed |
| US-20230406833-A1 | HERBICIDAL MALONAMIDES | BASF SE (DE) | 2023-12-21 | — | — | US | disclosed |
| US-4045427-A | POLYMERIZATION CATALYSTS | PENNWALT CORPORATION (US) | 1977-08-30 | — | — | US | disclosed |
| US-4042773-A | REACTION WITH POLYMERS | PENNWALT CORPORATION (US) | 1977-08-16 | — | — | US | disclosed |
| US-4000295-A | ARACHNICIDAL | ELI LILLY AND COMPANY (US) | 1976-12-28 | — | — | US | disclosed |
| US-3956269-A | POLYMERIZATION CATALYSTS | PENNWALT CORPORATION (US) | 1976-05-11 | — | — | US | disclosed |