Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 2/20 | 0.46 |
| ▸ | NOS1 | P29475 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | ADH1B | P00325 | 1/20 | 0.34 |
| ▸ | ADH1C | P00326 | 1/20 | 0.34 |
| ▸ | ADH1A | P07327 | 1/20 | 0.34 |
| ▸ | ADH4 | P08319 | 1/20 | 0.34 |
| ▸ | ADH7 | P40394 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10597539 | 1.00 | NOS2 (0.46) | NOS2NOS1CYP1A2ADH1BADH1C | |
| SCHEMBL10597549 | 1.00 | NOS2 (0.46) | NOS2NOS1CYP1A2ADH1BADH1C | |
| SCHEMBL818572 | 1.00 | NOS2 (0.46) | NOS2NOS1CYP1A2ADH1BADH1C | |
| SCHEMBL3931959 | 1.00 | NOS2 (0.46) | NOS2NOS1CYP1A2ADH1BADH1C | |
| SCHEMBL397148 | 0.97 | — | — | |
| SCHEMBL3932444 | 0.92 | — | — | |
| SCHEMBL8530783 | 0.87 | CYP1A2 (0.48) | NOS2NOS1CYP1A2SIGMAR1 | |
| SCHEMBL10512459 | 0.86 | NOS1 (0.41) | NOS2NOS1 | |
| SCHEMBL3935708 | 0.86 | — | — | |
| SCHEMBL19595018 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7312224-B2 | Pyrimidine derivatives | MERCK PATENT GMBH (DE) | 2007-12-25 | — | — | US | claimed |
| US-20040242595-A1 | Pyrimidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2004-12-02 | — | — | US | claimed |
| US-4371701-A | RUST INHIBITORS IN GASOLINE | STANDARD OIL COMPANY (INDIANA) (US) | 1983-02-01 | — | — | US | claimed |
| EP-3884019-A1 | HOME CARE COMPOSITIONS | Colgate-Palmolive Company (US) | 2021-09-29 | — | — | EP | disclosed |
| CN-113227340-A | Home care compositions | 高露洁-棕榄公司 | 2021-08-06 | — | — | CN | disclosed |
| US-11008533-B2 | Home care compositions | COLGATE-PALMOLIVE COMPANY (US) | 2021-05-18 | — | — | US | disclosed |
| US-20200208081-A1 | HOME CARE COMPOSITIONS | COLGATE-PALMOLIVE COMPANY (US) | 2020-07-02 | — | — | US | disclosed |
| WO-2020139335-A1 | HOME CARE COMPOSITIONS | COLGATE-PALMOLIVE COMPANY (US) | 2020-07-02 | — | — | WO | disclosed |
| CN-105874153-B | Modified hydrocarbon resins as fluid loss additives | 佐治亚-太平洋化工品有限公司 | 2019-04-30 | — | — | CN | disclosed |
| US-10005947-B2 | Modified hydrocarbon resins as fluid loss additives | INGEVITY SOUTH CAROLINA, LLC (US) | 2018-06-26 | — | — | US | disclosed |
| CN-106232783-A | Emulsifier component and using method thereof | 路博润公司 | 2016-12-14 | — | — | CN | disclosed |
| US-4433100-A | DICYCLOPENTADIENE, NON-AROMATIC UNSATURATED HYDROCARBON, FATTY OR ROSIN ACID | NEVILLE CHEMICAL COMPANY (US) | 1984-02-21 | — | — | US | disclosed |
| US-4405757-A | Macromolecular complexes of amidocarbonylic water-soluble polymers and square planar platinous and equivalent organometallics | HOWELL BOBBY A | 1983-09-20 | — | — | US | disclosed |
| US-4401799-A | ORGANOALUMINUM COMPOUND, ALIPHATIC ETHER, ALIPHATIC POLYCHLORIDE | TOA NENRYO KOGYO KABUSHIKI KAISHA (JP) | 1983-08-30 | — | — | US | disclosed |
| US-4282159-A | Preparation of alkylene oxides | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1981-08-04 | — | — | US | disclosed |
| US-4234720-A | Prostaglandin derivatives | ABBOTT LABORATORIES (US) | 1980-11-18 | — | — | US | disclosed |
| US-4188331-A | Prostaglandin derivatives | ABBOTT LABORATORIES (US) | 1980-02-12 | — | — | US | disclosed |
| US-4183826-A | Titanium trichloride catalyst and process for the production thereof | TOA NENRYO KOGYO KABUSHIKI KAISHA (JP) | 1980-01-15 | — | — | US | disclosed |
| US-4036896-A | FREE RADICAL CATALYST | UNIVERSAL OIL PRODUCTS COMPANY (US) | 1977-07-19 | — | — | US | disclosed |
| US-4010217-A | NITROSYL MOLYBDENUM OR TUNGSTEN COORDINATION CATALYST, ORGANOALUMINUM ADJUVANT | PHILLIPS PETROLEUM COMPANY (US) | 1977-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040242595-A1 | Pyrimidine derivatives | TYMP, DPYD, TYMS | NOS2 1714/4885NOS1 839/4885CYP1A2 361/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.