Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 3/20 | 0.49 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.49 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.49 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.49 |
| ▸ | TSPO | P30536 | 1/20 | 0.49 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | SPHK2 | Q9NRA0 | 4/20 | 0.48 |
| ▸ | SPHK1 | Q9NYA1 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | CETP | P11597 | 3/20 | 0.48 |
| ▸ | GMNN | O75496 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5276226 | 1.00 | S1PR1 (0.49) | S1PR1S1PR4S1PR3S1PR5ALDH1A1 | |
| SCHEMBL17976784 | 0.83 | CYP1A2 (0.36) | CYP2D6CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL21411327 | 0.83 | SGPL1 (0.54) | S1PR1S1PR4S1PR3S1PR5ALDH1A1 | |
| SCHEMBL12261535 | 0.80 | S1PR4 (0.34) | S1PR1S1PR4S1PR3S1PR5ALDH1A1 | |
| SCHEMBL14486068 | 0.80 | PLA2G4A (0.56) | ALDH1A1MEN1KMT2ACETPTHRB | |
| SCHEMBL16878592 | 0.79 | CYP1A2 (0.42) | ALDH1A1MEN1KMT2ASPHK2SPHK1 | |
| SCHEMBL16878593 | 0.79 | CYP1A2 (0.42) | ALDH1A1MEN1KMT2ASPHK2SPHK1 | |
| SCHEMBL13997496 | 0.79 | CYP2D6 (0.33) | S1PR1S1PR4S1PR3S1PR5ALDH1A1 | |
| SCHEMBL14994792 | 0.79 | CSNK1E (0.48) | ALDH1A1SPHK1MAPTCETPGMNN | |
| SCHEMBL24304751 | 0.78 | P2RY10 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1287006-B1 | ANTITUMORAL COMPOUNDS | PHARMA MAR SA (ES) | 2007-10-24 | — | — | EP | disclosed |
| US-7138547-B2 | Antitumoral compounds | PHARMA MAR, S.A. | 2006-11-21 | — | — | US | disclosed |
| US-20040048834-A1 | Antitumoral compounds | PHARMA MAR, S.A. (ES) | 2004-03-11 | — | — | US | disclosed |
| EP-1287006-A1 | ANTITUMORAL COMPOUNDS | PHARMA MAR, S.A. (ES) | 2003-03-05 | — | — | EP | disclosed |
| WO-2001094357-A1 | ANTITUMORAL COMPOUNDS | PHARMA MAR, S.A. (ES) | 2001-12-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040048834-A1 | Antitumoral compounds | HCCS, MSR1, SUCNR1 | S1PR1 14/4885S1PR4 56/4885S1PR3 19/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.