Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.34 |
| ▸ | CASP6 | P55212 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | ALB | P02768 | 1/20 | 0.34 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.34 |
| ▸ | TUBB | P07437 | 1/20 | 0.34 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5179509 | 1.00 | ALDH1A1 (0.41) | ALDH1A1POLBCHRM2CHRM1OPRM1 | |
| SCHEMBL967206 | 0.90 | ALDH1A1 (0.51) | ALDH1A1POLBCHRM2CHRM1OPRM1 | |
| SCHEMBL966606 | 0.90 | ALDH1A1 (0.51) | ALDH1A1POLBCHRM2CHRM1OPRM1 | |
| SCHEMBL967204 | 0.90 | ALDH1A1 (0.51) | ALDH1A1POLBCHRM2CHRM1OPRM1 | |
| SCHEMBL5178871 | 0.90 | ALDH1A1 (0.49) | ALDH1A1POLBCHRM2CHRM1OPRM1 | |
| SCHEMBL5277216 | 0.89 | KCNH2 (0.42) | ALDH1A1POLBOPRM1KDM4ELMNA | |
| SCHEMBL5282151 | 0.86 | KDM4E (0.46) | ALDH1A1POLBCHRM2CHRM1OPRM1 | |
| SCHEMBL5280465 | 0.85 | EPHX2 (0.36) | ALDH1A1POLBCHRM2CHRM1OPRM1 | |
| SCHEMBL5280454 | 0.85 | EPHX2 (0.36) | ALDH1A1POLBCHRM2CHRM1OPRM1 | |
| SCHEMBL5279342 | 0.85 | EPHX2 (0.36) | ALDH1A1POLBCHRM2CHRM1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1768973-B1 | SUBSTITUTED QUINOLONES | AICURIS GMBH & CO KG (DE) | 2007-12-05 | — | — | EP | disclosed |