Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.33 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5280454 | 1.00 | EPHX2 (0.36) | EPHX2HTR2AHTR2BFAAHDRD3 | |
| SCHEMBL5280465 | 1.00 | EPHX2 (0.36) | EPHX2HTR2AHTR2BFAAHDRD3 | |
| SCHEMBL5278268 | 0.92 | EPHX2 (0.36) | EPHX2DRD3P2RX7ALDH1A1POLB | |
| SCHEMBL5282397 | 0.92 | ALDH1A1 (0.40) | EPHX2HTR2AHTR2BFAAHDRD3 | |
| SCHEMBL12917296 | 0.91 | EPHX2 (0.40) | EPHX2HTR2AHTR2BALDH1A1POLB | |
| SCHEMBL964742 | 0.91 | EPHX2 (0.40) | EPHX2HTR2AHTR2BALDH1A1POLB | |
| SCHEMBL964823 | 0.91 | EPHX2 (0.40) | EPHX2HTR2AHTR2BALDH1A1POLB | |
| SCHEMBL5281789 | 0.89 | KDM4E (0.39) | P2RX7ALDH1A1POLBCHRM2CHRM1 | |
| SCHEMBL5284805 | 0.86 | ALDH1A1 (0.39) | HTR2AHTR2BP2RX7BCL2A1ALDH1A1 | |
| SCHEMBL5276352 | 0.85 | ALDH1A1 (0.41) | HTR2AHTR2BBCL2A1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1768973-B1 | SUBSTITUTED QUINOLONES | AICURIS GMBH & CO KG (DE) | 2007-12-05 | — | — | EP | disclosed |