Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 8/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 8/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 8/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 8/20 | 0.39 |
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | PDE5A | O76074 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.35 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.35 |
| ▸ | CCR1 | P32246 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3783903 | 0.84 | HTR1A (0.40) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| SCHEMBL238033 | 0.82 | HTR1A (0.41) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| SCHEMBL528353 | 0.82 | CHRM2 (0.35) | ADRA1DPDE5ALMNAKDM4EMAPT | |
| SCHEMBL241926 | 0.77 | HTR1A (0.40) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| SCHEMBL4986900 | 0.77 | HTR1A (0.49) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| SCHEMBL241335 | 0.76 | HTR1A (0.44) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| SCHEMBL13993581 | 0.76 | PDE5A (0.44) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| SCHEMBL241983 | 0.76 | FERMT2 (0.51) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| SCHEMBL242051 | 0.74 | MEN1 (0.55) | MEN1LMNAPOLBKMT2AMITF | |
| SCHEMBL243582 | 0.74 | FERMT2 (0.61) | HTR1AADRA1DADRA1AADRA1BFERMT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012015901-A1 | METHODS FOR TREATING GASTRIC AND PANCREATIC MALIGNANCIES | GENZYME CORPORATION (US) | 2012-02-02 | — | — | WO | disclosed |