Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 7/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 7/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 7/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 7/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CLK1 | P49759 | 1/20 | 0.37 |
| ▸ | CCR1 | P32246 | 1/20 | 0.37 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.37 |
| ▸ | EHMT1 | Q9H9B1 | 2/20 | 0.37 |
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4986900 | 0.85 | HTR1A (0.49) | HTR1AADRA1DADRA1AADRA1BCCR1 | |
| SCHEMBL527640 | 0.84 | HTR1A (0.39) | HTR1AADRA1DADRA1AADRA1BKDM4E | |
| SCHEMBL238033 | 0.81 | HTR1A (0.41) | HTR1AADRA1DADRA1AADRA1BKDM4E | |
| SCHEMBL3712435 | 0.81 | CHRM2 (0.39) | ADRA1DKDM4ELMNAHSD17B10HPGD | |
| SCHEMBL13993581 | 0.78 | PDE5A (0.44) | HTR1AADRA1DADRA1AADRA1BKDM4E | |
| SCHEMBL241000 | 0.78 | KDM4E (0.61) | HTR1AADRA1DADRA1AADRA1BKDM4E | |
| SCHEMBL241926 | 0.77 | HTR1A (0.40) | HTR1AADRA1DADRA1AADRA1BKDM4E | |
| SCHEMBL241335 | 0.75 | HTR1A (0.44) | HTR1AADRA1DADRA1AADRA1BKDM4E | |
| SCHEMBL243582 | 0.75 | FERMT2 (0.61) | HTR1AADRA1DADRA1AADRA1BKDM4E | |
| SCHEMBL241983 | 0.75 | FERMT2 (0.51) | HTR1AADRA1DADRA1AADRA1BKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010088544-A1 | METHODS TO TREAT CANCER | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2010-08-05 | — | — | WO | disclosed |