Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.64 |
| ▸ | RAB9A | P51151 | 3/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27626461 | 0.86 | NPC1 (0.62) | NPC1RAB9ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL213877 | 0.86 | PTPN7 (0.51) | NPC1RAB9ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL27798824 | 0.85 | ALDH1A1 (0.62) | NPC1RAB9ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL31255362 | 0.85 | ALDH1A1 (0.62) | NPC1RAB9ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL8864730 | 0.84 | NPC1 (0.60) | NPC1RAB9ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL10176161 | 0.84 | MAPT (0.62) | NPC1RAB9ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL16285732 | 0.84 | MAPT (0.49) | NPC1RAB9ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL3314184 | 0.82 | LMNA (0.51) | NPC1RAB9ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL10870559 | 0.82 | MAPT (0.71) | NPC1RAB9ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL8746685 | 0.82 | MAPT (0.62) | NPC1RAB9ASMN1; SMN2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1857440-A1 | Novel compounds, isomer thereof, or pharmaceutically acceptable salts thereof as vanilloid receptor antagonist; and pharmaceutical compositions containing the same | Amorepacific Corporation (KR) | 2007-11-21 | — | — | EP | disclosed |
| EP-0069585-B1 | COLOR-FORMING SULFONAMIDODIPHENYLAMINES, PHOTOGRAPHIC ELEMENTS CONTAINING THEM AND CORRESPONDING SULFONIMIDE DYES | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1985-07-03 | — | — | EP | disclosed |
| US-4499304-A | COLOR PHOTOGRAPHY;SILVER HALIDE EMULSIONS; PRINTING PLATES; IMAGES | EASTMAN KODAK COMPANY (US) | 1985-02-12 | — | — | US | disclosed |