Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ACACB | O00763 | 2/20 | 0.43 |
| ▸ | KHK | P50053 | 2/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | BCL2A1 | Q16548 | 2/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GHSR | Q92847 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2249128 | 1.00 | MAPT (0.46) | MAPTACACBKHKMCHR1CHRM2 | |
| SCHEMBL14922242 | 0.80 | ADRB1 (0.47) | MAPTHTR2CALDH1A1 | |
| SCHEMBL2248371 | 0.79 | MAPT (0.46) | MAPTKHKBCL2A1ALDH1A1 | |
| SCHEMBL5271800 | 0.79 | MAPT (0.46) | MAPTKHKBCL2A1ALDH1A1 | |
| SCHEMBL29671585 | 0.75 | S100B (0.43) | MAPTACACBMCHR1CHRM2CHRM1 | |
| SCHEMBL14922288 | 0.74 | KDM4E (0.49) | MAPTACACBALDH1A1 | |
| SCHEMBL20159005 | 0.74 | MAPT (0.49) | MAPTACACBKHKHTR2CBCL2A1 | |
| SCHEMBL8110875 | 0.74 | MAPT (0.49) | MAPTACACBKHKHTR2CBCL2A1 | |
| SCHEMBL8271862 | 0.73 | CHEK1 (0.46) | MAPTACACBKHKBCL2A1CHEK1 | |
| SCHEMBL2252356 | 0.73 | CHEK1 (0.46) | MAPTACACBKHKBCL2A1CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1771421-A1 | N-HYDROXYAMIDE DERIVATIVES AND USE THEREOF | Applied Research Systems ARS Holding N.V. (AN) | 2007-04-11 | — | — | EP | disclosed |
| WO-2006010751-A1 | N-HYDROXYAMIDE DERIVATIVES AND USE THEREOF | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2006-02-02 | — | — | WO | disclosed |