SCHEMBL5276786

SCHEMBL5276786

C=CC(=O)CO[Si](CCCNC)(OC)OC

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ZDHHC20 Q5W0Z9 1/20 0.33
ZDHHC2 Q9UIJ5 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27784237 0.84 TSHR (0.38) ZDHHC20ZDHHC2
SCHEMBL30540357 0.83 TSHR (0.32)
SCHEMBL31407861 0.81 ALDH1A1 (0.31)
SCHEMBL30771905 0.80 ALDH1A1 (0.31) ZDHHC20ZDHHC2
SCHEMBL30540351 0.79 TSHR (0.34)
SCHEMBL5072266 0.79 TSHR (0.39) ZDHHC20ZDHHC2
SCHEMBL29057829 0.75 ALDH1A1 (0.37)
SCHEMBL29613948 0.75 TSHR (0.41)
SCHEMBL28306478 0.73
SCHEMBL56162 0.72 LMNA (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1858982-A1 SILICONE EMULSION, METHOD OF PREPARING SAME, AND COSMETIC INGREDIENT Dow Corning Corporation (US) 2007-11-28 EP disclosed
WO-2006102010-A1 SILICONE EMULSION, METHOD OF PREPARING SAME, AND COSMETIC INGREDIENT DOW CORNING CORPORATION (US) 2006-09-28 WO disclosed