SCHEMBL5277464

SCHEMBL5277464

O=C(O)CC(C(=O)O)C1CC2CCC1C2

nearest known ligand 0.43

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.40
LMNA P02545 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
POLB P06746 2/20 0.36
ALDH1A1 P00352 3/20 0.35
L3MBTL1 Q9Y468 1/20 0.34
KMT2A Q03164 1/20 0.33
HSD11B1 P28845 1/20 0.33
EPHX2 P34913 1/20 0.33
CYP1A2 P05177 1/20 0.33
TSHR P16473 1/20 0.33
NPC1 O15118 1/20 0.33
ATM Q13315 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11672951 0.80 HPGD (0.51) HPGDLMNASMN1; SMN2POLBALDH1A1
SCHEMBL27854878 0.76 TDP1 (0.42) SMN1; SMN2ALDH1A1CYP1A2TSHR
SCHEMBL28523189 0.76 HPGD (0.42) HPGDLMNASMN1; SMN2POLBALDH1A1
SCHEMBL28164399 0.75 HPGD (0.45) HPGDLMNASMN1; SMN2POLBALDH1A1
SCHEMBL27333987 0.73 CYP1A2 (0.37) SMN1; SMN2ALDH1A1CYP1A2TSHR
SCHEMBL22986628 0.72 HPGD (0.42) HPGDLMNASMN1; SMN2POLBALDH1A1
SCHEMBL5988116 0.72 SLC1A2 (0.52) HPGDLMNASMN1; SMN2POLBKMT2A
SCHEMBL31332785 0.72 HPGD (0.42) HPGDLMNASMN1; SMN2POLBALDH1A1
SCHEMBL1088756 0.72 HPGD (0.50) HPGDLMNASMN1; SMN2POLBALDH1A1
SCHEMBL25946739 0.72 HPGD (0.42) HPGDLMNASMN1; SMN2POLBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114716591-B Catalyst component for propylene polymerization, preparation method and application thereof 任丘市利和科技发展有限公司 2024-05-28 CN disclosed
CN-108219295-B Polypropylene composition, polypropylene sheet and process for producing the same, and secondary molded article 富比食品包装有限公司 2021-09-07 CN disclosed
CN-112204055-A Polypropylene composition and molded article 巴塞尔聚烯烃意大利有限公司 2021-01-08 CN disclosed
US-20190169328-A1 OLEFIN POLYMERIZATION CATALYST CARRIER, SOLID CATALYST COMPONENT AND USE THEREOF RENQIU LIHE TECH LTD (CN) 2019-06-06 US disclosed
EP-1525231-B1 CATALYST SYSTEM FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE SRL (IT) 2007-12-05 EP disclosed
EP-1088009-B1 COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE SRL (IT) 2006-08-02 EP disclosed
EP-1525231-A1 CATALYST SYSTEM FOR THE POLYMERIZATION OF OLEFINS Basell Poliolefine Italia S.P.A. (IT) 2005-04-27 EP disclosed
US-20050032633-A1 Propylene polymers BASELL POLIOLEFINE ITALIA S.P.A. (IT) 2005-02-10 US disclosed
US-6818583-B1 HIGH YIELDS AND HIGH ISOTACTIC INDEX; COMPRISING MG, TI, HALOGEN AND A SUCCINATE ELECTRON DONOR BASELL POLIOLEFINE ITALIA S.P.A. (IT) 2004-11-16 US disclosed
WO-2004005359-A1 CATALYST SYSTEM FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.P.A. (IT) 2004-01-15 WO disclosed
EP-1088009-A1 COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS Basell Technology Company B.V. (NL) 2001-04-04 EP disclosed
WO-2000063261-A1 COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS BASELL TECHNOLOGY COMPANY B.V. (NL) 2000-10-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190169328-A1 OLEFIN POLYMERIZATION CATALYST CARRIER, SOLID CATALYST COMPONENT AND USE THEREOF COG2, GTF2I, POF1B HPGD 2103/4885LMNA 2302/4885SMN1; SMN2 1503/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.