SCHEMBL5277779

SCHEMBL5277779

CCCc1nnn(C)c1C(F)(F)F

nearest known ligand 0.40

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
GABRB3 P28472 10/20 0.40
GABRA2 P47869 4/20 0.40
GABRB2 P47870 4/20 0.40
MAOB P27338 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5281447 0.89 MAOB (0.39) GABRB3GABRA2GABRB2MAOB
SCHEMBL5275463 0.85 GABRB3 (0.35) GABRB3GABRA2GABRB2MAOB
SCHEMBL5279494 0.84 GABRB3 (0.37) GABRB3GABRA2GABRB2
SCHEMBL5277157 0.82 MAOB (0.33) GABRB3GABRA2GABRB2MAOBSMN1; SMN2
SCHEMBL5277711 0.81 GABRB3 (0.38) GABRB3GABRA2GABRB2
SCHEMBL5272715 0.81 MAOB (0.38) GABRB3GABRA2GABRB2MAOBSMN1; SMN2
SCHEMBL5283221 0.79 GABRB3 (0.39) GABRB3GABRA2GABRB2
SCHEMBL5280231 0.79 SLC9A1 (0.38) GABRB3GABRA2GABRB2
SCHEMBL5279388 0.78 GABRB3 (0.33) GABRB3GABRA2GABRB2MAOB
SCHEMBL5275565 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1859781-A2 Brightening and/or colouring agent with triazoles Henkel Kommanditgesellschaft auf Aktien (DE) 2007-11-28 EP disclosed