Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IP6K1 | Q92551 | 7/20 | 0.51 |
| ▸ | PARP1 | P09874 | 9/20 | 0.50 |
| ▸ | BCL2 | P10415 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | IGF1R | P08069 | 2/20 | 0.40 |
| ▸ | PIM1 | P11309 | 2/20 | 0.40 |
| ▸ | CLK2 | P49760 | 2/20 | 0.40 |
| ▸ | GSK3A | P49840 | 2/20 | 0.40 |
| ▸ | GSK3B | P49841 | 2/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | PAK4 | O96013 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | RET | P07949 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18128478 | 0.78 | IP6K1 (0.56) | IP6K1PARP1BCL2MCL1IGF1R | |
| SCHEMBL525865 | 0.75 | PARP1 (0.49) | IP6K1PARP1PIM1ALDH1A1PIM2 | |
| SCHEMBL18130618 | 0.74 | IP6K1 (0.56) | IP6K1PARP1BCL2MCL1IGF1R | |
| SCHEMBL3659063 | 0.72 | PARP1 (0.61) | IP6K1PARP1PIM1ACVR1ALDH1A1 | |
| SCHEMBL8568798 | 0.69 | PARP1 (0.61) | IP6K1PARP1BCL2MCL1IGF1R | |
| SCHEMBL526730 | 0.67 | PARP1 (1.00) | IP6K1PARP1BCL2MCL1IGF1R | |
| SCHEMBL527342 | 0.66 | PGR (0.34) | PARP1ALDH1A1 | |
| SCHEMBL15846231 | 0.65 | IP6K1 (0.48) | IP6K1PARP1BCL2MCL1MAP4K4 | |
| SCHEMBL12068369 | 0.65 | PARP1 (0.51) | IP6K1PARP1BCL2MCL1IGF1R | |
| SCHEMBL31559173 | 0.65 | PARP1 (0.47) | IP6K1PARP1BCL2MCL1IGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014109-A1 | HETEROCYCLIC SULFONAMIDES AS INHIBITORS OF TRANSFER RNA SYNTHETASE FOR USE AS ANTIBACTERIAL AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | disclosed |