Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | GPR139 | Q6DWJ6 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL527881 | 1.00 | KMT2A (0.50) | KMT2AALDH1A1HTTMEN1KDM4E | |
| SCHEMBL12505324 | 0.92 | HPGD (0.53) | KMT2AALDH1A1HTTMEN1KDM4E | |
| SCHEMBL526554 | 0.87 | ALDH1A1 (0.52) | KMT2AALDH1A1HTTMEN1KDM4E | |
| SCHEMBL12505318 | 0.85 | ALDH1A1 (0.48) | KMT2AALDH1A1HTTMEN1KDM4E | |
| SCHEMBL528313 | 0.84 | KMT2A (0.47) | KMT2AALDH1A1HTTMEN1KDM4E | |
| SCHEMBL528312 | 0.84 | KMT2A (0.47) | KMT2AALDH1A1HTTMEN1KDM4E | |
| SCHEMBL526239 | 0.83 | ALDH1A1 (0.48) | KMT2AALDH1A1HTTMEN1KDM4E | |
| SCHEMBL528620 | 0.83 | ALDH1A1 (0.48) | KMT2AALDH1A1HTTMEN1KDM4E | |
| SCHEMBL528621 | 0.83 | ALDH1A1 (0.48) | KMT2AALDH1A1HTTMEN1KDM4E | |
| SCHEMBL527992 | 0.81 | GPR139 (0.51) | KMT2AALDH1A1MEN1KDM4EGPR139 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2598493-A1 | MATRIX METALLOPROTEINASE INHIBITORS | Ranbaxy Laboratories Limited (IN) | 2013-06-05 | — | — | EP | disclosed |
| WO-2012014114-A1 | MATRIX METALLOPROTEINASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | disclosed |