Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | TOP2A | P11388 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.31 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5276739 | 0.90 | SLC9A1 (0.37) | SMN1; SMN2KMT2AMEN1HPGDALDH1A1 | |
| SCHEMBL5281712 | 0.87 | SLC9A1 (0.40) | SMN1; SMN2KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL5279772 | 0.86 | SMN1; SMN2 (0.36) | SMN1; SMN2KMT2AMEN1HPGDALDH1A1 | |
| SCHEMBL5285281 | 0.81 | ALDH1A1 (0.36) | SMN1; SMN2KMT2AMEN1HPGDALDH1A1 | |
| SCHEMBL5276496 | 0.81 | SMN1; SMN2 (0.38) | SMN1; SMN2KMT2AMEN1HPGDALDH1A1 | |
| SCHEMBL5279213 | 0.79 | KDM4E (0.42) | SMN1; SMN2KMT2AMEN1HPGDALDH1A1 | |
| SCHEMBL5279006 | 0.79 | GRM2 (0.37) | SMN1; SMN2KMT2AMEN1HPGDALDH1A1 | |
| SCHEMBL5280639 | 0.79 | MAPT (0.37) | SMN1; SMN2KMT2AMEN1HPGDALDH1A1 | |
| SCHEMBL5284361 | 0.79 | ALDH1A1 (0.33) | SMN1; SMN2KMT2AMEN1HPGDALDH1A1 | |
| SCHEMBL5277962 | 0.78 | SMN1; SMN2 (0.36) | SMN1; SMN2KMT2AMEN1HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1859781-A2 | Brightening and/or colouring agent with triazoles | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-11-28 | — | — | EP | disclosed |