Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | PAM | P19021 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5007271 | 0.86 | KDM4E (0.37) | L3MBTL1POLBSMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL2926028 | 0.85 | HDAC3 (0.41) | SMN1; SMN2FFAR1ALDH1A1MAPT | |
| SCHEMBL74038 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL5009250 | 0.78 | SPHK2 (0.37) | POLBSMN1; SMN2KMT2AMEN1KDM4E | |
| SCHEMBL3524878 | 0.75 | SLC6A2 (0.32) | — | |
| SCHEMBL1698739 | 0.74 | AKR1B1 (0.46) | PAMFFAR1AKR1B1 | |
| SCHEMBL230546 | 0.73 | CTRB1 (0.36) | AKR1B1 | |
| SCHEMBL5359874 | 0.73 | MAPK8 (0.43) | L3MBTL1SMN1; SMN2ALDH1A1KDM4ETDP1 | |
| SCHEMBL6474578 | 0.72 | P2RX7 (0.33) | ALDH1A1KDM4E | |
| SCHEMBL1656726 | 0.72 | POLB (0.45) | POLBALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1857440-A1 | Novel compounds, isomer thereof, or pharmaceutically acceptable salts thereof as vanilloid receptor antagonist; and pharmaceutical compositions containing the same | Amorepacific Corporation (KR) | 2007-11-21 | — | — | EP | disclosed |