Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4989345 | 1.00 | MGAM (0.37) | MGAMGAASIMGAM2L3MBTL1 | |
| SCHEMBL4450222 | 1.00 | MGAM (0.37) | MGAMGAASIMGAM2L3MBTL1 | |
| SCHEMBL4452755 | 0.89 | MGAM (0.41) | MGAMGAASIMGAM2L3MBTL1 | |
| SCHEMBL6404270 | 0.89 | MGAM (0.41) | MGAMGAASIMGAM2L3MBTL1 | |
| SCHEMBL4989784 | 0.89 | MGAM (0.41) | MGAMGAASIMGAM2L3MBTL1 | |
| SCHEMBL4940668 | 0.81 | ALDH1A1 (0.34) | POLBALDH1A1MAPTCYP1A2 | |
| SCHEMBL4940673 | 0.81 | ALDH1A1 (0.34) | POLBALDH1A1MAPTCYP1A2 | |
| SCHEMBL4564435 | 0.80 | MGAM (0.45) | MGAMGAASIMGAM2L3MBTL1 | |
| SCHEMBL1405748 | 0.76 | MGAM (0.43) | MGAMGAASIMGAM2L3MBTL1 | |
| SCHEMBL18828587 | 0.75 | MGAM (0.44) | MGAMGAASIMGAM2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1863780-A1 | PREPARATION OF OPTICALLY PURE BETA-AMINO ACIDS HAVING AFFINITY FOR THE ALPHA-2-DELTA PROTEIN | Pharmacia & Upjohn Company LLC (US) | 2007-12-12 | — | — | EP | disclosed |
| WO-2006100568-A1 | PREPARATION OF OPTICALLY PURE BETA-AMINO ACIDS HAVING AFFINITY FOR THE ALPHA-2-DELTA PROTEIN | PHARMACIA & UPJOHN COMPANY LLC (US) | 2006-09-28 | — | — | WO | disclosed |