Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 7/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.45 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | BRAF | P15056 | 1/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL528754 | 0.91 | MAPT (0.56) | SMN1; SMN2CYP1A2CYP2C19GFERMAPT | |
| SCHEMBL527900 | 0.90 | MAPT (0.60) | SMN1; SMN2MAPTLMNANPSR1KDM4E | |
| SCHEMBL528823 | 0.89 | MAPT (0.53) | SMN1; SMN2MAPTLMNANPSR1KDM4E | |
| SCHEMBL528087 | 0.89 | KMT2A (0.55) | SMN1; SMN2MAPTLMNANPSR1KDM4E | |
| SCHEMBL529226 | 0.89 | SMN1; SMN2 (0.48) | SMN1; SMN2CYP1A2CYP2C19GFERMAPT | |
| SCHEMBL528111 | 0.88 | MAPT (0.48) | SMN1; SMN2MAPTLMNANPSR1KDM4E | |
| SCHEMBL528590 | 0.88 | MAPT (0.63) | SMN1; SMN2CYP1A2CYP2C19GFERMAPT | |
| SCHEMBL529579 | 0.87 | MAPT (0.61) | SMN1; SMN2MAPTLMNAKDM4ENPC1 | |
| SCHEMBL528642 | 0.86 | LMNA (0.48) | SMN1; SMN2MAPTLMNANPSR1POLB | |
| SCHEMBL528856 | 0.85 | MAPT (0.49) | SMN1; SMN2MAPTLMNANPSR1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014127-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | disclosed |