Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 0.63 |
| ▸ | LMNA | P02545 | 5/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL529003 | 0.91 | MAPT (0.66) | MAPTLMNAALDH1A1KDM4EKMT2A | |
| SCHEMBL528683 | 0.91 | MAPT (0.77) | MAPTLMNAALDH1A1KDM4EKMT2A | |
| SCHEMBL531055 | 0.91 | MAPT (0.71) | MAPTLMNAALDH1A1KDM4EHTT | |
| SCHEMBL528499 | 0.89 | MAPT (0.63) | MAPTLMNAALDH1A1KDM4EKMT2A | |
| SCHEMBL528754 | 0.89 | MAPT (0.56) | MAPTLMNAALDH1A1KDM4EKMT2A | |
| SCHEMBL528010 | 0.88 | SMN1; SMN2 (0.52) | MAPTLMNAALDH1A1KDM4EKMT2A | |
| SCHEMBL529032 | 0.87 | MAPT (0.77) | MAPTLMNAALDH1A1KDM4EKMT2A | |
| SCHEMBL527884 | 0.87 | MAPT (0.74) | MAPTLMNAALDH1A1KDM4EHTT | |
| SCHEMBL527969 | 0.86 | MAPT (0.60) | MAPTLMNAALDH1A1KDM4EKMT2A | |
| SCHEMBL528794 | 0.86 | MAPT (0.62) | MAPTLMNAALDH1A1KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014127-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | disclosed |