SCHEMBL528013

SCHEMBL528013

CC(OC(N)=O)C(C)(Br)Br

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.39
TSHR P16473 3/20 0.39
CHRM2 P08172 1/20 0.39
CHRM4 P08173 1/20 0.39
CHRM5 P08912 1/20 0.39
CHRM1 P11229 1/20 0.39
CHRM3 P20309 1/20 0.39
CYP2C9 P11712 1/20 0.39
MAPT P10636 1/20 0.38
HSD17B10 Q99714 1/20 0.33
CYP3A4 P08684 1/20 0.32
NFKB1 P19838 1/20 0.32
ADRA1A P35348 1/20 0.32
RAB9A P51151 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5665771 0.80 LMNA (0.41) LMNATSHRCHRM2CHRM4CHRM5
SCHEMBL19500214 0.80 LMNA (0.41) LMNATSHRCHRM2CHRM4CHRM5
SCHEMBL16987582 0.80 LMNA (0.41) LMNATSHRCHRM2CHRM4CHRM5
SCHEMBL5107294 0.78 LMNA (0.40) LMNATSHRCHRM2CHRM4CHRM5
SCHEMBL5107291 0.78 LMNA (0.40) LMNATSHRCHRM2CHRM4CHRM5
SCHEMBL29021075 0.77 LMNA (0.36) LMNATSHRCHRM2CHRM4CHRM5
SCHEMBL12493193 0.76 LMNA (0.39) LMNATSHRCHRM2CHRM4CHRM5
SCHEMBL28343392 0.76
SCHEMBL13278856 0.74 LMNA (0.38) LMNATSHRCHRM2CHRM4CHRM5
SCHEMBL27891086 0.74 LMNA (0.38) LMNATSHRCHRM2CHRM4CHRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 296 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109963833-B Process for the preparation of mono-protected alpha, omega-diaminoalkanes 拜奥迪斯私人有限公司 2022-02-22 CN claimed
CN-118355117-A Oligonucleotide compositions and methods thereof 波涛生命科学有限公司 2024-07-16 CN disclosed
CN-118307529-A 2, 3-Dihydronaphthalene-embedded m-diazabenzene compound, synthesis method, pharmaceutical composition and application thereof 中国科学院上海药物研究所 2024-07-09 CN disclosed
CN-118139629-A Compositions and methods for editing MECP2 transcripts 波涛生命科学有限公司 2024-06-04 CN disclosed
CN-118139977-A Double-stranded oligonucleotide compositions and methods relating thereto 波涛生命科学有限公司 2024-06-04 CN disclosed
CN-118076584-A Esters of retinoids and bakuchiol and formulations thereof 康纳根有限公司 2024-05-24 CN disclosed
CN-118055926-A ROCK2 inhibitors and uses thereof 哈佛大学的校长及成员们 2024-05-17 CN disclosed
CN-117965536-A Oligonucleotide compositions and methods thereof 波涛生命科学有限公司 2024-05-03 CN disclosed
CN-113444086-B Ezh2 inhibitors and uses thereof 达纳-法伯癌症研究所股份有限公司 2024-04-30 CN disclosed
CN-117924310-A Macrocyclic compounds and uses thereof 哈佛大学的校长及成员们 2024-04-26 CN disclosed
WO-2011156774-A2 MULTIVALENT GLYCOPEPTIDE CONSTRUCTS AND USES THEREOF SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) 2011-12-15 WO disclosed
EP-2389357-A1 ANTI-INFLAMMATORY COMPLEXES Signum Biosciences, Inc. (US) 2011-11-30 EP disclosed
US-8038936-B2 Cooking device with deodorization LG ELECTRONICS INC. (KR) 2011-10-18 US disclosed
WO-2011119887-A1 RNA INTERFERENCE IN DERMAL AND FIBROTIC INDICATIONS RXI PHARMACEUTICALS CORPORATION (US) 2011-09-29 WO disclosed
WO-2011119549-A1 TRIOXACARCINS AND USES THEREOF PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2011-09-29 WO disclosed
EP-2365962-A2 AMINOALCOHOL LIPIDOIDS AND USES THEREOF Massachusetts Institute of Technology (US) 2011-09-21 EP disclosed
WO-2011073967-A1 A BIOMATERIAL VYSERA BIOMEDICAL LIMITED (IE) 2011-06-23 WO disclosed
WO-2010090845-A1 ANTI-INFLAMMATORY COMPLEXES SIGNUM BIOSCIENCES, INC. (US) 2010-08-12 WO disclosed
WO-2010053572-A2 AMINOALCOHOL LIPIDOIDS AND USES THEREOF MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2010-05-14 WO disclosed
WO-2007008226-A2 PALLADIUM-CATALYZED CARBON-CARBON BOND FORMING REACTIONS THE PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2007-01-18 WO disclosed