Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16987582 | 1.00 | LMNA (0.41) | LMNATSHRCHRM2CHRM4CHRM5 | |
| SCHEMBL19500214 | 1.00 | LMNA (0.41) | LMNATSHRCHRM2CHRM4CHRM5 | |
| Methacrylic Acid SCHEMBL28556602 | 0.85 | TDP1 (0.36) | LMNATSHRCHRM2CHRM4CHRM5 | |
| Acrylic Acid SCHEMBL28553802 | 0.85 | LMNA (0.39) | LMNATSHRCHRM2CHRM4CHRM5 | |
| SCHEMBL5107291 | 0.82 | LMNA (0.40) | LMNATSHRCHRM2CHRM4CHRM5 | |
| SCHEMBL5107294 | 0.82 | LMNA (0.40) | LMNATSHRCHRM2CHRM4CHRM5 | |
| SCHEMBL12493193 | 0.80 | LMNA (0.39) | LMNATSHRCHRM2CHRM4CHRM5 | |
| SCHEMBL528013 | 0.80 | LMNA (0.39) | LMNATSHRCHRM2CHRM4CHRM5 | |
| SCHEMBL30889139 | 0.79 | TSHR (0.32) | TSHRGRM1 | |
| SCHEMBL13278856 | 0.78 | LMNA (0.38) | LMNATSHRCHRM2CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811402-A | ANTICOAGULANTS, THROMBIN INHIBITORS | ELI LILLY AND COMPANY (US) | 1998-09-22 | — | — | US | claimed |
| EP-0796866-A1 | Antithrombotic diamides | ELI LILLY AND COMPANY (US) | 1997-09-24 | — | — | EP | claimed |
| US-4276211-A | COLOR STABILIZATION OF IODOALKYNE CARBAMATES WITH EPOXIDES | TROY CHEMICAL CORPORATION (US) | 1981-06-30 | — | — | US | claimed |
| WO-2024094637-A1 | PROCESS FOR THE PREPARATION OF CYCLIC KETONES | ARXADA AG (CH) | 2024-05-10 | — | — | WO | disclosed |
| CN-117897386-A | Benzopyran derivatives and uses thereof | 斯帕克生物制药有限公司 | 2024-04-16 | — | — | CN | disclosed |
| CN-114615999-B | Drug antibody conjugates | 法马马有限公司 | 2024-03-08 | — | — | CN | disclosed |
| CN-116942663-A | Compounds for the treatment of HBV | 葛兰素史克知识产权开发有限公司 | 2023-10-27 | — | — | CN | disclosed |
| CN-116947836-A | Method for preparing furazanobenzimidazole and crystal forms thereof | 巴斯利尔药物国际股份公司 | 2023-10-27 | — | — | CN | disclosed |
| CN-110536890-B | Method for preparing furazanobenzimidazole and crystal forms thereof | 巴斯利尔药物国际股份公司 | 2023-08-15 | — | — | CN | disclosed |
| CN-116323638-A | Stapled peptides and methods thereof | 弗格制药有限公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-115108927-A | Crystal forms and synthesis methods of (2R,6R) -hydroxynorketamine and (2S,6S) -hydroxynorketamine | 美国政府健康及人类服务部 | 2022-09-27 | — | — | CN | disclosed |
| US-5331006-A | Cholecystokinin, antisecretory agents | WARNER-LAMBERT COMPANY (US) | 1994-07-19 | — | — | US | disclosed |
| US-5229379-A | Gamma-aminobutyric acid antagonists | CIBA-GEIGY CORPORATION (US) | 1993-07-20 | — | — | US | disclosed |
| US-5159046-A | Modified 1,5-naphthalene diisocyanate containing urea and biuret groups; using water and organic solvent mixture | BAYER AKTIENGESELLSCHAFT (DE) | 1992-10-27 | — | — | US | disclosed |
| US-4918185-A | Process for carbon-carbon bond formation at the C-4 position of 3-acylaminoazetidinones and products and starting materials therefor | ELI LILLY AND COMPANY (US) | 1990-04-17 | — | — | US | disclosed |
| US-4835180-A | N-(ω-cyanoalkyl)aminophenols and use as inhibitors of lipoxygenase activity | STERLING DRUG INC. (US) | 1989-05-30 | — | — | US | disclosed |
| US-4831013-A | BENZODIAZEPINE RECEPTOR ANTAGONISTS | CIBA-GEIGY CORPORATION (US) | 1989-05-16 | — | — | US | disclosed |
| US-4771135-A | ANTIBIOTIC INTERMEDIATES | ELI LILLY AND COMPANY (US) | 1988-09-13 | — | — | US | disclosed |
| EP-0262618-A2 | N-(omega)-cyanoalkyl)aminophenols, and their preparation | STERLING DRUG INC. (US) | 1988-04-06 | — | — | EP | disclosed |
| EP-0163452-A1 | A novel process for carbon-carbon bond formation at the C-4 position of 3-acylaminoazetidinones | ELI LILLY AND COMPANY (US) | 1985-12-04 | — | — | EP | disclosed |