Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5282850 | 0.90 | L3MBTL1 (0.57) | L3MBTL1ALDH1A1TDP1CYP1A2CYP2C9 | |
| SCHEMBL5277000 | 0.88 | ALDH1A1 (0.55) | L3MBTL1ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL5282772 | 0.88 | L3MBTL1 (0.56) | L3MBTL1ALDH1A1TDP1CYP1A2CYP2C9 | |
| SCHEMBL5279608 | 0.86 | ALDH1A1 (0.71) | L3MBTL1ALDH1A1TDP1CYP1A2CYP2C9 | |
| SCHEMBL5114560 | 0.85 | TDP1 (0.69) | L3MBTL1ALDH1A1TDP1CYP1A2CYP2C9 | |
| SCHEMBL5294553 | 0.84 | ALDH1A1 (0.50) | L3MBTL1ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL5277536 | 0.83 | L3MBTL1 (0.52) | L3MBTL1ALDH1A1TDP1CYP1A2CYP2C9 | |
| SCHEMBL5283006 | 0.83 | L3MBTL1 (0.54) | L3MBTL1ALDH1A1TDP1CYP1A2CYP2C9 | |
| SCHEMBL5282184 | 0.82 | L3MBTL1 (0.50) | L3MBTL1ALDH1A1TDP1CYP1A2CYP2C9 | |
| SCHEMBL5285487 | 0.82 | ALDH1A1 (0.52) | L3MBTL1ALDH1A1TDP1CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1866289-A1 | PYRIMIDINE CARBOXYLIC ACID DERIVATIVES AND USE THEREOF | Bayer HealthCare AG (DE) | 2007-12-19 | — | — | EP | disclosed |
| WO-2006097220-A1 | PYRIMIDINE CARBOXYLIC ACID DERIVATIVES AND USE THEREOF | BAYER HEALTHCARE AG (DE) | 2006-09-21 | — | — | WO | disclosed |