Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 9/20 | 0.49 |
| ▸ | ACHE | P22303 | 6/20 | 0.49 |
| ▸ | BRS3 | P32247 | 1/20 | 0.46 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.45 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.45 |
| ▸ | ITGAL | P20701 | 2/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.45 |
| ▸ | TACR2 | P21452 | 3/20 | 0.45 |
| ▸ | TACR1 | P25103 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5280288 | 0.93 | KMT2A (0.51) | BCHEACHETACR2TACR1KMT2A | |
| SCHEMBL5280283 | 0.93 | KMT2A (0.51) | BCHEACHETACR2TACR1KMT2A | |
| SCHEMBL5282971 | 0.90 | BCHE (0.47) | BCHEACHEBRS3CHRM4 | |
| SCHEMBL5282975 | 0.90 | BCHE (0.47) | BCHEACHEBRS3CHRM4 | |
| SCHEMBL5282166 | 0.86 | ACHE (0.53) | BCHEACHECHRM4KMT2A | |
| SCHEMBL5282667 | 0.85 | BCHE (0.55) | BCHEACHECHRM4TACR1KMT2A | |
| SCHEMBL5289480 | 0.85 | BCHE (0.56) | BCHEACHECHRM4TACR1KMT2A | |
| SCHEMBL5278655 | 0.83 | BCHE (0.59) | BCHEACHE | |
| SCHEMBL5291489 | 0.82 | BCHE (0.52) | BCHEACHETACR1KMT2A | |
| SCHEMBL5279913 | 0.80 | BCHE (0.60) | BCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1863804-A1 | INHIBITORS OF HISTONE DEACETYLASE | Methylgene, Inc. (CA) | 2007-12-12 | — | — | EP | claimed |
| WO-2006102760-A1 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE INC. (CA) | 2006-10-05 | — | — | WO | claimed |