Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 7/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 3/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.36 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5323618 | 0.89 | SLC7A5 (0.43) | SLC7A5HRH1TAAR1KCNH2SLC6A4 | |
| SCHEMBL27438936 | 0.85 | LTA4H (0.44) | SLC7A5SLC6A4 | |
| SCHEMBL9992781 | 0.84 | LTA4H (0.44) | SLC7A5HTR2AHRH1KCNH2SLC6A4 | |
| SCHEMBL27671364 | 0.82 | SLC6A4 (0.37) | SLC7A5SLC6A4 | |
| SCHEMBL27510040 | 0.82 | LTA4H (0.43) | SLC7A5HTR2AHRH1KCNH2SLC6A4 | |
| SCHEMBL28199477 | 0.82 | LTA4H (0.43) | SLC7A5HTR2AHRH1KCNH2SLC6A4 | |
| SCHEMBL8766939 | 0.82 | LTA4H (0.43) | SLC7A5HTR2AHRH1KCNH2SLC6A4 | |
| SCHEMBL28174310 | 0.82 | LTA4H (0.43) | SLC7A5HTR2AHRH1KCNH2SLC6A4 | |
| SCHEMBL5286697 | 0.81 | TAAR1 (0.39) | SLC7A5HTR2ATAAR1SLC6A4 | |
| SCHEMBL20449085 | 0.81 | TAAR1 (0.39) | SLC7A5HTR2ATAAR1SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1756107-A2 | ARYL-SUBSTITUTED PIPERAZINE DERIVATIVES | NEUROGEN CORPORATION (US) | 2007-02-28 | — | — | EP | claimed |
| WO-2006009789-A2 | ARYL-SUBSTITUTED PIPERAZINE DERIVATIVES | NEUROGEN CORPORATION (US) | 2006-01-26 | — | — | WO | claimed |