SCHEMBL5280550

SCHEMBL5280550

CC(C)=N/N=c1\sc2cc(O)ccc2n1C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.44
RAB9A P51151 6/20 0.44
NPC1 O15118 5/20 0.44
SMN1; SMN2 Q16637 5/20 0.44
HTT P42858 1/20 0.44
KMT2A Q03164 3/20 0.41
MEN1 O00255 2/20 0.41
ATM Q13315 1/20 0.40
ALDH1A1 P00352 3/20 0.39
TP53 P04637 2/20 0.39
TSHR P16473 2/20 0.39
PKM P14618 1/20 0.39
FPR1 P21462 1/20 0.39
RXFP1 Q9HBX9 2/20 0.37
POLB P06746 2/20 0.37
KDM4E B2RXH2 2/20 0.37
TNKS O95271 1/20 0.37
PARP1 P09874 1/20 0.37
PARP15 Q460N3 1/20 0.37
PARP14 Q460N5 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5280552 1.00 MAPT (0.44) MAPTRAB9ANPC1SMN1; SMN2HTT
SCHEMBL5281276 0.85 RAB9A (0.56) MAPTRAB9ANPC1SMN1; SMN2HTT
SCHEMBL5281281 0.85 RAB9A (0.56) MAPTRAB9ANPC1SMN1; SMN2HTT
SCHEMBL5282896 0.84 THRB (0.51) MAPTRAB9ANPC1SMN1; SMN2HTT
SCHEMBL5282900 0.84 THRB (0.51) MAPTRAB9ANPC1SMN1; SMN2HTT
SCHEMBL5281751 0.80 RXFP1 (0.44) MAPTRAB9ANPC1SMN1; SMN2HTT
SCHEMBL5277822 0.80 RXFP1 (0.44) MAPTRAB9ANPC1SMN1; SMN2HTT
SCHEMBL4615522 0.80 NPC1 (0.43) MAPTRAB9ANPC1SMN1; SMN2KMT2A
SCHEMBL5278390 0.80 MAPT (0.64) MAPTRAB9ANPC1SMN1; SMN2HTT
SCHEMBL5278396 0.80 MAPT (0.64) MAPTRAB9ANPC1SMN1; SMN2HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1599178-B1 MEANS AND METHOD FOR DYEING KERATIN FIBRES WELLA AG (DE) 2007-12-19 EP claimed
US-20060070190-A1 Means and method for dyeing keratin fibres KOYO SEIKO CO., LTD. (JP) 2006-04-06 US claimed
EP-1599178-B1 MEANS AND METHOD FOR DYEING KERATIN FIBRES WELLA AG (DE) 2007-12-19 EP disclosed
US-7294151-B2 Means and method for dyeing keratin fibres WELLA AG (DE) 2007-11-13 US disclosed
US-20060070190-A1 Means and method for dyeing keratin fibres KOYO SEIKO CO., LTD. (JP) 2006-04-06 US disclosed
EP-1599178-A1 MEANS AND METHOD FOR DYEING KERATIN FIBRES Wella Aktiengesellschaft (DE) 2005-11-30 EP disclosed
WO-2004078151-A1 MEANS AND METHOD FOR DYEING KERATIN FIBRES WELLA AKTIENGESELLSCHAFT (DE) 2004-09-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060070190-A1 Means and method for dyeing keratin fibres KRT18, KLK5, KIT MAPT 1807/4885RAB9A 3143/4885NPC1 4843/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.