SCHEMBL5280805

SCHEMBL5280805

CCCc1c(C(Cl)(Cl)Cl)nnn1C

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.35
GABRB3 P28472 4/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5278028 0.89 MAOB (0.46) MAOB
SCHEMBL5275998 0.85 MAOB (0.31) MAOBGABRB3
SCHEMBL5284287 0.84 MAOB (0.30) MAOB
SCHEMBL5278770 0.82 MAOB (0.33) MAOB
SCHEMBL5275272 0.82 GABRB3 (0.38) MAOBGABRB3
SCHEMBL5277246 0.81 SLC9A1 (0.35) GABRB3
SCHEMBL5279254 0.79 GRIA1 (0.31) GABRB3
SCHEMBL5284846 0.79 SLC9A1 (0.38)
SCHEMBL5277063 0.78 GABRB3 (0.33) MAOBGABRB3
SCHEMBL5282958 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1859781-A2 Brightening and/or colouring agent with triazoles Henkel Kommanditgesellschaft auf Aktien (DE) 2007-11-28 EP disclosed