Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5285430 | 0.87 | THRA (0.41) | THRATHRB | |
| SCHEMBL5274822 | 0.84 | THRA (0.37) | THRATHRB | |
| SCHEMBL5283822 | 0.83 | THRB (0.57) | THRATHRB | |
| SCHEMBL5281233 | 0.81 | THRA (0.50) | THRATHRB | |
| SCHEMBL5281913 | 0.79 | THRA (0.59) | THRATHRB | |
| SCHEMBL5291072 | 0.78 | THRA (0.46) | THRATHRB | |
| SCHEMBL5283377 | 0.78 | THRA (0.37) | THRATHRB | |
| SCHEMBL5282022 | 0.77 | BACE1 (0.48) | THRATHRB | |
| SCHEMBL5964697 | 0.74 | THRA (0.49) | THRATHRB | |
| SCHEMBL5282649 | 0.73 | THRB (0.63) | THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1862450-A2 | Novel compounds | KARO BIO AB (SE) | 2007-12-05 | — | — | EP | disclosed |
| EP-1537073-B1 | BENZAMIDE OR PHENYLACETAMIDE DERIVATIVES USEFUL AS THYROID RECEPTOR LIGANDS | KAROBIO AB (SE) | 2007-09-12 | — | — | EP | disclosed |
| EP-1537073-A2 | BENZAMIDE OR PHENYLACETAMIDE DERIVATIVES USEFUL AS THYROID RECEPTOR LIGANDS | KARO BIO AB (SE) | 2005-06-08 | — | — | EP | disclosed |
| WO-2004007430-A2 | BENZAMIDE OR PHENYLACETAMIDE DERIVATIVES USEFUL AS THYROID RECEPTOR LIGANDS | KARO BIO AB (SE) | 2004-01-22 | — | — | WO | disclosed |