Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.55 |
| ▸ | HTT | P42858 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | PKM | P14618 | 3/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | HTR6 | P50406 | 4/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | FAM20C | Q8IXL6 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28864522 | 0.86 | LMNA (0.68) | LMNAHTTSMN1; SMN2PKMMAPK1 | |
| SCHEMBL6048148 | 0.86 | CYP19A1 (0.65) | LMNAHTTSMN1; SMN2PKMMAPK1 | |
| SCHEMBL6350411 | 0.85 | HTR6 (0.65) | LMNAHTTSMN1; SMN2PKMMAPK1 | |
| SCHEMBL213547 | 0.85 | LMNA (0.77) | LMNAHTTSMN1; SMN2PKMMAPK1 | |
| SCHEMBL6073370 | 0.84 | CA12 (0.59) | LMNAHTTSMN1; SMN2PKMMAPK1 | |
| SCHEMBL6341219 | 0.83 | LMNA (0.79) | LMNAHTTSMN1; SMN2PKMMAPK1 | |
| SCHEMBL5289106 | 0.81 | SMN1; SMN2 (0.65) | LMNAHTTSMN1; SMN2PKMMAPK1 | |
| SCHEMBL6349559 | 0.81 | MAPK1 (0.67) | LMNAHTTSMN1; SMN2PKMMAPK1 | |
| SCHEMBL6343830 | 0.81 | MEN1 (0.67) | LMNAHTTSMN1; SMN2PKMMAPK1 | |
| SCHEMBL2215125 | 0.79 | CA1 (0.62) | LMNAHTTSMN1; SMN2PKMMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112876388-B | GPR120 agonist and preparation method and application thereof | 山东大学 | 2023-03-31 | — | — | CN | disclosed |
| CN-112876388-A | GPR120 agonist and preparation method and application thereof | 山东大学 | 2021-06-01 | — | — | CN | disclosed |
| EP-1863804-A1 | INHIBITORS OF HISTONE DEACETYLASE | Methylgene, Inc. (CA) | 2007-12-12 | — | — | EP | disclosed |
| US-20060264415-A1 | Inhibitors of histone deacetylase | METHYLGENE INC. | 2006-11-23 | — | — | US | disclosed |
| WO-2006102760-A1 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE INC. (CA) | 2006-10-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060264415-A1 | Inhibitors of histone deacetylase | HDAC1, HDAC3, HDAC11 | LMNA 851/4885HTT 846/4885SMN1; SMN2 3733/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.