SCHEMBL5281478

SCHEMBL5281478

CC(C)(C)C(C)(C)C(C)(C)OCNc1nc(N)nc(N)n1

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA9 Q16790 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL725070 0.82 CA1 (0.34) CA1CA2CA9
SCHEMBL11526425 0.73
SCHEMBL5075318 0.71 CA1 (0.33) CA1CA2CA9
SCHEMBL545236 0.71 CA1 (0.37) CA1CA2CA9
SCHEMBL3105245 0.71 CA1 (0.39) CA1CA2CA9
SCHEMBL8401061 0.70
SCHEMBL963512 0.68 TLR8 (0.36) CA1CA2CA9
SCHEMBL28072000 0.68 NPC1 (0.35) CA1CA2CA9
SCHEMBL16978943 0.67 IDH1 (0.49) CA1CA2CA9
SCHEMBL4444984 0.67 NPC1 (0.35) CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1348001-B1 CLEAR LACQUER COAT BOLLIG & KEMPER GMBH & CO KG (DE) 2007-12-05 EP disclosed
EP-1341833-B1 ACRYLATE-BASED COATING COMPOSITION CONTAINING FLUOROMODIFIED POLYMERS BOLLIG & KEMPER GMBH & CO KG (DE) 2006-01-25 EP disclosed
US-6939601-B2 obtained by applying an unpigmented intermediate coat to a substrate to be coated,crosslinking the intermediate coat and forming an intermediate coat layer,applying an unpigmented top-coat , crosslinking; flexibility; automobiles BOLLIG & KEMPER GMBH & CO. KG (DE) 2005-09-06 US disclosed
EP-1501830-A1 7-ARYL-3,9-DIAZABICYCLO[3.3.1]NON-6-ENE DERIVATIVES AND THEIR USE AS RENIN INHIBITORS IN THE TREATMENT OF HYPERTENSION, CARDIOVASCULAR OR RENAL DISEASES Actelion Pharmaceuticals Ltd. (CH) 2005-02-02 EP disclosed
US-20040121160-A1 obtainable by applying unpigmented intermediate coat to substrate to be coated, crosslinking intermediate coat, applying unpigmented top-coat to intermediate coat layer, crosslinking top coat; automobiles; impact resistance, gloss PPG COATINGS DEUTSCHLAND GMBH (DE) 2004-06-24 US disclosed
US-20040063851-A1 Acrylate-based coating composition containing fluoromodified polymers BOLLIG & KEMPER GMBH & CO. KG (DE) 2004-04-01 US disclosed
WO-2003093267-A1 7-ARYL-3,9-DIAZABICYCLO(3.3.1)NON-6-ENE DERIVATIVES AND THEIR USE AS RENIN INHIBITORS IN THE TREATMENT OF HYPERTENSION, CARDIOVASCULAR OR RENAL DISEASES ACTELION PHARMACEUTICALS LTD (CH) 2003-11-13 WO disclosed
EP-1348001-A1 CLEAR LACQUER COAT Bollig & Kemper GmbH & Co. KG (DE) 2003-10-01 EP disclosed
EP-1341833-A1 ACRYLATE-BASED COATING COMPOSITION CONTAINING FLUOROMODIFIED POLYMERS Bollig & Kemper GmbH & Co. KG (DE) 2003-09-10 EP disclosed
WO-2002044235-A1 ACRYLATE-BASED COATING COMPOSITION CONTAINING FLUOROMODIFIED POLYMERS BOLLIG & KEMPER GMBH & CO. KG (DE) 2002-06-06 WO disclosed
WO-2002044237-A1 CLEAR LACQUER COAT BOLLIG & KEMPER GMBH & CO. KG (DE) 2002-06-06 WO disclosed
US-6005056-A REACTION PRODUCT OF EPOXY GROUP CONTAINING ACRYLIC COPOLYMERWITH A CARBOXYL GROUP CONTAINING POLYCYCLOALIPHATIC COMPOUND;CLEAR COATS FOR AUTOMOBILES; HIGH GLOSS BOLLIG & KEMPER KG (DE) 1999-12-21 US disclosed
EP-0813552-B1 MODIFIED ACRYL COPOLYMER BOLLIG & KEMPER GMBH & CO KG (DE) 1998-12-23 EP disclosed
EP-0813552-A1 MODIFIED ACRYL COPOLYMER BOLLIG & KEMPER KG (DE) 1997-12-29 EP disclosed
WO-1996028478-A1 MODIFIED ACRYL COPOLYMER BOLLIG & KEMPER KG (DE) 1996-09-19 WO disclosed
US-4192937-A Process for the preparation of isocyanate polyaddition products which have hydroxyl groups in side chains BAYER AKTIENGESELLSCHAFT (DE) 1980-03-11 US disclosed