SCHEMBL963512

SCHEMBL963512

CCOCNc1nc(N)nc(N)n1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TLR8 Q9NR97 4/20 0.36
CA1 P00915 2/20 0.35
CA2 P00918 2/20 0.35
CA9 Q16790 2/20 0.35
SMN1; SMN2 Q16637 5/20 0.35
NPC1 O15118 3/20 0.33
RAB9A P51151 3/20 0.33
TLR7 Q9NYK1 2/20 0.33
TP53 P04637 1/20 0.33
GLA P06280 1/20 0.33
MAPK1 P28482 1/20 0.33
MAPT P10636 2/20 0.33
JAK2 O60674 1/20 0.33
HTT P42858 1/20 0.33
LMNA P02545 2/20 0.33
KDM4E B2RXH2 1/20 0.32
NFKB1 P19838 1/20 0.32
CASP3 P42574 1/20 0.32
CDK9 P50750 1/20 0.32
CDK5 Q00535 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17915969 0.96 TLR8 (0.36) TLR8SMN1; SMN2NPC1RAB9ATLR7
Hexane SCHEMBL11397490 0.93 TLR8 (0.42) TLR8SMN1; SMN2NPC1RAB9ATLR7
Lindane SCHEMBL1672734 0.91 NPC1 (0.32) TLR8CA1CA2CA9SMN1; SMN2
SCHEMBL8130295 0.90 SMN1; SMN2 (0.33) TLR8CA1CA2CA9SMN1; SMN2
SCHEMBL3105245 0.87 CA1 (0.39) CA1CA2CA9SMN1; SMN2NPC1
SCHEMBL5954738 0.84 LMNA (0.41) SMN1; SMN2MAPK1HTTLMNAALDH1A1
SCHEMBL3981799 0.84 CA1 (0.37) TLR8CA1CA2CA9SMN1; SMN2
SCHEMBL408240 0.81 TLR8 (0.40) TLR8CA1CA2CA9SMN1; SMN2
SCHEMBL28661180 0.81 CA1 (0.36) CA1CA2CA9NPSR1
SCHEMBL32675851 0.80 HTR7 (0.40) CA1CA2CA9SMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3877459-A1 POLYMER NETWORK FORMING SILANE COMPOSITIONS Momentive Performance Materials Inc. (US) 2021-09-15 EP claimed
CN-111433270-A High modulus rubber compositions comprising vulcanization ultra-accelerators 米其林集团总公司 2020-07-17 CN claimed
CN-111433047-A High modulus rubber compositions comprising an effective sulfur crosslinking system 米其林集团总公司 2020-07-17 CN claimed
CN-1815364-A Light-sensitive composition for chemical amplitude type negative PS plate and chemical amplitude type negative PS plate thereof UNIV BEIJING NORMAL (CN) 2006-08-09 CN claimed
US-4409077-A Ultraviolet radiation curable coating composition SUMITOMO CHEMICAL CO., LTD. (JP) 1983-10-11 US claimed
EP-4621021-A1 SURFACE TREATMENT COMPOSITION FOR ZINC ALLOY PLATED STEEL SHEET, ZINC ALLOY PLATED STEEL SHEET SURFACE-TREATED USING SAME AND METHOD FOR MANUFACTURING SAME POSCO Co., Ltd (KR) 2025-09-24 EP disclosed
CN-120153036-A Surface treatment composition for galvanized alloy steel sheet, galvanized alloy steel sheet surface-treated with the composition, and method for producing the same 浦项股份有限公司 2025-06-13 CN disclosed
US-20250104915-A1 RELEASE FILM AND METHOD FOR MANUFACTURING MULTILAYER ELECTRONIC COMPONENT USING THE SAME SAMSUNG ELECTRO-MECHANICS CO., LTD. (KR) 2025-03-27 US disclosed
CN-119659129-A Release film and method for manufacturing multilayer electronic component using the same 三星电机株式会社 2025-03-21 CN disclosed
WO-2024107018-A1 SURFACE TREATMENT COMPOSITION FOR ZINC ALLOY PLATED STEEL SHEET, ZINC ALLOY PLATED STEEL SHEET SURFACE-TREATED USING SAME AND METHOD FOR MANUFACTURING SAME 주식회사 포스코 2024-05-23 WO disclosed
CN-110007563-B Negative photosensitive resin composition, spacer, protective film, and liquid crystal display element 奇美实业股份有限公司 2024-04-02 CN disclosed
WO-2024015956-A1 RUBBER COMPOSITIONS CONTAINING PHLOROGLUCINOLIC RESINS FOR USE IN TIRE TREADS OF HEAVY VEHICLES SUMITOMO CHEMICAL ADVANCED TECHNOLOGIES, LLC, D.B.A. SUMIKA ELECTRONIC MATERIALS (US) 2024-01-18 WO disclosed
CN-1148055-A Sulfur-containing urethane-based resin composition, its resin, and optical element and lens comprising resin thereof MITSUI TOATSU CHEMICALS (JP) 1997-04-23 CN disclosed
EP-0154789-A1 Polyfunctional phenolic reaction product, a process for its preparation and its use THE DOW CHEMICAL COMPANY (US) 1985-09-18 EP disclosed
US-4515835-A HYDROXY-FUNCTIONAL ADDITION POLYMER, REACTIVE DILUENT ROHM AND HAAS COMPANY (US) 1985-05-07 US disclosed
US-4409077-A Ultraviolet radiation curable coating composition SUMITOMO CHEMICAL CO., LTD. (JP) 1983-10-11 US disclosed
EP-0016086-A4 NON MELT-DRIP FLAME RETARDANT POLYCARBONATE ARTICLES. GEN ELECTRIC (US) 1980-10-16 EP disclosed
EP-0016086-A1 NON MELT-DRIP FLAME RETARDANT POLYCARBONATE ARTICLES. GEN ELECTRIC (US) 1980-10-01 EP disclosed
WO-1980000143-A1 NON MELT-DRIP FLAME RETARDANT POLYCARBONATE COMPOSITION GEN ELECTRIC (US) 1980-02-07 WO disclosed
US-4125678-A Radiation polymerizable compositions THE SHERWIN-WILLIAMS COMPANY (US) 1978-11-14 US disclosed