Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | GPR35 | Q9HC97 | 4/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.46 |
| ▸ | MAP2 | P11137 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13174695 | 0.79 | KDM4E (0.67) | KDM4EALDH1A1HPGDMEN1HTT | |
| SCHEMBL3947323 | 0.78 | BRD4 (0.54) | KDM4EALDH1A1HPGDMEN1HTT | |
| SCHEMBL4930867 | 0.78 | UQCRB (0.56) | KDM4EALDH1A1HPGDMEN1HTT | |
| SCHEMBL3945167 | 0.78 | BRD4 (0.61) | KDM4EALDH1A1HPGDMEN1HTT | |
| SCHEMBL4762476 | 0.78 | BRD4 (0.53) | KDM4EALDH1A1HPGDMEN1HTT | |
| SCHEMBL4933597 | 0.77 | GPR35 (0.53) | ALDH1A1MEN1GFERKMT2AGPR35 | |
| SCHEMBL3946651 | 0.77 | BRD4 (0.53) | ALDH1A1MEN1GFERKMT2AGPR35 | |
| SCHEMBL5151357 | 0.77 | KDM4E (0.51) | KDM4EALDH1A1HPGDMEN1HTT | |
| SCHEMBL4933945 | 0.77 | MAPT (0.59) | ALDH1A1HPGDMEN1GFERKMT2A | |
| Dimethylamine SCHEMBL4931369 | 0.76 | BRD4 (0.59) | KDM4EALDH1A1HPGDMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778632-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | Biolipox AB (SE) | 2007-05-02 | — | — | EP | disclosed |
| WO-2005123673-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2005-12-29 | — | — | WO | disclosed |