Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.45 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | FABP4 | P15090 | 1/20 | 0.40 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29620333 | 0.83 | KDM4E (0.71) | KDM4ERAB9AAGTR1ALDH1A1HSD17B10 | |
| SCHEMBL341645 | 0.83 | KDM4E (0.71) | KDM4ERAB9AAGTR1ALDH1A1HSD17B10 | |
| SCHEMBL16181442 | 0.82 | FABP4 (0.50) | KDM4ERAB9AAGTR1ALDH1A1HSD17B10 | |
| Water SCHEMBL7614858 | 0.81 | KDM4E (0.69) | KDM4ERAB9AAGTR1ALDH1A1HSD17B10 | |
| Methane SCHEMBL2342916 | 0.81 | KDM4E (0.69) | KDM4ERAB9AAGTR1ALDH1A1HSD17B10 | |
| SCHEMBL14574944 | 0.81 | PARP1 (0.48) | KDM4ERAB9AAGTR1ALDH1A1HSD17B10 | |
| SCHEMBL7824620 | 0.81 | PBRM1 (0.55) | ALDH1A1PARP1PBRM1POLBKMT2A | |
| SCHEMBL4607469 | 0.81 | KDM4E (0.49) | KDM4ERAB9AAGTR1ALDH1A1HPGD | |
| Potassium SCHEMBL14574757 | 0.79 | PARP1 (0.47) | KDM4ERAB9AAGTR1ALDH1A1HSD17B10 | |
| SCHEMBL13783620 | 0.79 | KDM6B (0.53) | KDM4ERAB9AAGTR1ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1866416-A2 | DELIVERY SYSTEMS AND METHODS FOR DIAGNOSING AND TREATING CARDIOVASCULAR DISEASES | Medstar Health Inc. (US) | 2007-12-19 | — | — | EP | claimed |
| WO-2006102395-A2 | DELIVERY SYSTEMS AND METHODS FOR DIAGNOSING AND TREATING CARDIOVASCULAR DISEASES | MEDSTAR HEALTH INC (US) | 2006-09-28 | — | — | WO | claimed |
| US-11059886-B1 | Methods and compositions for treating inflammatory or autoimmune diseases or conditions using GRM8 activators | FLAGSHIP PIONEERING INNOVATIONS V, INC. (US) | 2021-07-13 | — | — | US | disclosed |
| EP-2580215-A2 | 8-(2'-HETEROCYCYL)PYRIDO[2.3-D]PYRIMIDIN-7(8H)-ONES FOR THE TREATMENT OF CNS DISORDERS | Afraxis, Inc. (US) | 2013-04-17 | — | — | EP | disclosed |
| WO-2011156775-A2 | 8-(2'-HETEROCYCYL)PYRIDO[2.3-D]PYRIMIDIN-7(8H)-ONES FOR THE TREATMENT OF CNS DISORDERS | AFRAXIS, INC. (US) | 2011-12-15 | — | — | WO | disclosed |