SCHEMBL341645

SCHEMBL341645

O=C(O)CNc1ccccc1C(=O)O

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.71
AGTR1 P30556 1/20 0.71
RAB9A P51151 1/20 0.71
ALDH1A1 P00352 5/20 0.68
HPGD P15428 2/20 0.68
HSD17B10 Q99714 2/20 0.68
POLB P06746 2/20 0.57
L3MBTL1 Q9Y468 2/20 0.57
CTDSP1 Q9GZU7 1/20 0.57
FABP4 P15090 2/20 0.52
KMT2A Q03164 4/20 0.50
ALOX15 P16050 1/20 0.50
CLCN2 P51788 1/20 0.49
CFD P00746 1/20 0.49
FABP3 P05413 1/20 0.49
FABP5 Q01469 1/20 0.49
PLK1 P53350 1/20 0.48
RECQL P46063 1/20 0.47
MEN1 O00255 2/20 0.47
LMNA P02545 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29620333 1.00 KDM4E (0.71) KDM4EAGTR1RAB9AALDH1A1HPGD
Water SCHEMBL7614858 0.98 KDM4E (0.69) KDM4EAGTR1RAB9AALDH1A1HPGD
Methane SCHEMBL2342916 0.98 KDM4E (0.69) KDM4EAGTR1RAB9AALDH1A1HPGD
SCHEMBL5692314 0.85 PARP1 (0.51) KDM4EAGTR1RAB9AALDH1A1HPGD
SCHEMBL5698321 0.85 KDM4E (0.67) KDM4EAGTR1RAB9AALDH1A1HPGD
SCHEMBL5707628 0.85 POLB (0.56) KDM4EAGTR1RAB9AALDH1A1HPGD
SCHEMBL690246 0.85 KDM4E (0.53) KDM4EAGTR1RAB9AALDH1A1HPGD
SCHEMBL4270045 0.85 KDM4E (0.67) KDM4EAGTR1RAB9AALDH1A1HPGD
SCHEMBL1499127 0.85 AGTR1 (0.60) KDM4EAGTR1RAB9AALDH1A1HPGD
SCHEMBL1170114 0.83 ALDH1A1 (0.67) KDM4EAGTR1RAB9AALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 342 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2604697-B1 Triprenyl phenol compounds, process for their production and use as thrombolysis enhancer UNIV TOKYO AGRICULTURE & TECHNOLOGY TLO CO LTD (JP) 2015-07-01 EP claimed
EP-2604697-A1 Triprenyl phenol compounds, process for their production and use as thrombolysis enhancer Tokyo University of Agriculture and Technology TLO (JP) 2013-06-19 EP claimed
CN-101142214-B Ocaperidone salts and pharmaceutical compositions containing the same JANSSEN PHARMACEUTICA NV 2011-02-23 CN claimed
EP-1888577-B1 OCAPERIDONE SALTS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME JANSSEN PHARMACEUTICA NV (BE) 2008-11-12 EP claimed
US-20080200479-A1 Ocaperidone Salts and Pharmaceutical Compositions Containing the Same NEURO3D S.A. (FR) 2008-08-21 US claimed
CN-101142214-A Ocaperidone salts and pharmaceutical compositions containing the same JANSSEN PHARMACEUTICA NV (BE) 2008-03-12 CN claimed
EP-1888577-A1 OCAPERIDONE SALTS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME JANSSEN PHARMACEUTICA N.V. (BE) 2008-02-20 EP claimed
WO-2006090285-A1 OCAPERIDONE SALTS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME JANSSEN PHARMACEUTICA N.V. (BE) 2006-08-31 WO claimed
WO-2000062771-A1 USES OF PHENYLGLYCINE DERIVATIVES THE UAB RESEARCH FOUNDATION (US) 2000-10-26 WO claimed
US-20260085042-A1 METHOD FOR PREPARING INDIGO OR A SUBSTITUTED DERIVATIVE THEREOF PILI (FR) 2026-03-26 US disclosed
US-20260085042-A1 METHOD FOR PREPARING INDIGO OR A SUBSTITUTED DERIVATIVE THEREOF PILI (FR) 2026-03-26 US disclosed
EP-3459441-B1 SLOW INTRAVENTRICULAR DELIVERY GENZYME CORP (US) 2025-09-03 EP disclosed
EP-4540322-A1 METHOD FOR PREPARING INDIGO OR A SUBSTITUTED DERIVATIVE THEREOF PILI (FR) 2025-04-23 EP disclosed
US-20240409514-A1 METHODS FOR INHIBITING NATIVE AND PROMISCUOUS UPTAKE OF MONOAMINE NEUROTRANSMITTERS ETHISMOS RESEARCH, INC. (US) 2024-12-12 US disclosed
US-4305858-A Process for the preparation of stable ionic dispersions of polyisocyanate-polyaddition products in hydroxyl containing compounds BAYER AKTIENGESELLSCHAFT (DE) 1981-12-15 US disclosed
US-4197219-A Aqueous polyurethane-phenolic-formaldehyde resin emulsions for use as adhesives, primers and surface coatings LORD CORPORATION (US) 1980-04-08 US disclosed
US-4184990-A Process for the preparation of stable dispersions of polyisocyanate-polyaddition products in a hydroxyl containing compound as dispersing agent BAYER AKTIENGESELLSCHAFT (DE) 1980-01-22 US disclosed
US-4147680-A Production of polyurethane resins using as active hydrogen material a stable dispersion of ionic polyisocyanate-polyaddition products in hydroxyl containing compounds as a dispersing agent BAYER AKTIENGESELLSCHAFT (DE) 1979-04-03 US disclosed
US-4092275-A Polyurethane resins prepared from active hydrogen containing material which is a dispersion of polyisocyanate-polyaddition products in hydroxyl containing compounds as dispersing agents BAYER AKTIENGESELLSCHAFT (DT) 1978-05-30 US disclosed
US-3970601-A COATINGS BAYER AKTIENGESELLSCHAFT (DT) 1976-07-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260085042-A1 METHOD FOR PREPARING INDIGO OR A SUBSTITUTED DERIVATIVE THEREOF TDO2, IDH2, IDH3A KDM4E 3070/4885AGTR1 1073/4885RAB9A 2450/4885
US-20080200479-A1 Ocaperidone Salts and Pharmaceutical Compositions Containing the Same OTC, PMP22, OLA1 KDM4E 4254/4885AGTR1 862/4885RAB9A 3401/4885
US-20240409514-A1 METHODS FOR INHIBITING NATIVE AND PROMISCUOUS UPTAKE OF MONOAMINE NEUROTRANSMITTERS SLC18A2, SLC6A2, SLC18A3 KDM4E 2426/4885AGTR1 638/4885RAB9A 1314/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.