SCHEMBL528216

SCHEMBL528216

C=C(CC(O)COCCC[Si](C)(C)C(C)(C)C)C(N)=O

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2C19 P33261 1/20 0.32
HTT P42858 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18204281 0.83 L3MBTL1 (0.33) CYP1A2CYP3A4CYP2C19HTT
SCHEMBL1982425 0.81
SCHEMBL1982426 0.81
SCHEMBL527709 0.81 CYP1A2 (0.32) CYP1A2CYP3A4CYP2C19HTT
SCHEMBL1562994 0.78 HTT (0.53) CYP1A2CYP3A4CYP2C19HTT
SCHEMBL508267 0.76 CASR (0.31) CYP1A2CYP3A4CYP2C19
SCHEMBL2096192 0.76
SCHEMBL2096185 0.76
SCHEMBL508829 0.75 USP2 (0.31) CYP1A2CYP3A4CYP2C19HTT
SCHEMBL27841095 0.75 USP2 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2598936-A1 METHOD FOR MAKING UV-ABSORBING OPHTHALMIC LENSES Novartis AG (CH) 2013-06-05 EP disclosed
WO-2012015639-A1 METHOD FOR MAKING UV-ABSORBING OPHTHALMIC LENSES NOVARTIS AG (CH) 2012-02-02 WO disclosed