Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 7/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.32 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylic Acid SCHEMBL2041101 | 0.95 | TSHR (0.53) | TSHRTHRBHPGDCYP1A2CYP3A4 | |
| Acrylic Acid SCHEMBL9388200 | 0.90 | TSHR (0.50) | TSHRTHRBHPGDCYP1A2CYP3A4 | |
| Acrylic Acid SCHEMBL5291299 | 0.90 | TSHR (0.44) | TSHRTHRBHPGDCYP3A4ACHE | |
| Acrylic Acid SCHEMBL2389210 | 0.87 | TSHR (0.47) | TSHRTHRBHPGDCYP1A2CYP3A4 | |
| Butadiene SCHEMBL28287926 | 0.86 | TSHR (0.56) | TSHRTHRBHPGDCYP1A2CYP3A4 | |
| SCHEMBL331327 | 0.86 | TSHR (0.62) | TSHRTHRBCYP1A2CYP3A4CYP2D6 | |
| Methacrylic Acid SCHEMBL31299771 | 0.84 | TSHR (0.57) | TSHRTHRBCYP1A2CYP3A4CYP2D6 | |
| Acrylic Acid SCHEMBL2808323 | 0.84 | ZDHHC20 (0.56) | TSHRACHEZDHHC20ZDHHC2 | |
| Carbamic Acid SCHEMBL27513552 | 0.83 | TSHR (0.61) | TSHRTHRBPOLBAPEX1HTT | |
| Acrylic Acid SCHEMBL2048764 | 0.83 | TSHR (0.45) | TSHRTHRBHPGDACHEPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007002880-A2 | METHOD OF ENHANCED DRUG APPLICATION | JR CHEM, LLC (US) | 2007-01-04 | — | — | WO | claimed |
| WO-2007002880-A2 | METHOD OF ENHANCED DRUG APPLICATION | JR CHEM, LLC (US) | 2007-01-04 | — | — | WO | disclosed |