Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | FAAH | O00519 | 3/20 | 0.38 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.35 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.35 |
| ▸ | DGKA | P23743 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylic Acid SCHEMBL2389210 | 0.92 | TSHR (0.47) | TSHRFAAHSOAT1MEN1KMT2A | |
| Acrylic Acid SCHEMBL578219 | 0.91 | TSHR (0.44) | TSHRFAAHSOAT1MEN1KMT2A | |
| Acrylic Acid SCHEMBL5282179 | 0.90 | TSHR (0.48) | TSHRCYP1A2CYP3A4CYP2C19KDM4E | |
| Acrylic Acid SCHEMBL2041101 | 0.90 | TSHR (0.53) | TSHRCYP1A2CYP3A4CYP2C19KDM4E | |
| Acrylic Acid SCHEMBL2048764 | 0.87 | TSHR (0.45) | TSHRTHRBEPHX2HPGDPOLB | |
| Acrylic Acid SCHEMBL2808323 | 0.85 | ZDHHC20 (0.56) | TSHRFAAHZDHHC20ZDHHC2EPHX2 | |
| Carbamic Acid SCHEMBL27513552 | 0.85 | TSHR (0.61) | TSHRFAAHTHRBPOLBAPEX1 | |
| Butadiene SCHEMBL28287926 | 0.82 | TSHR (0.56) | TSHRCYP1A2CYP3A4CYP2C19KDM4E | |
| SCHEMBL8052195 | 0.82 | TSHR (0.69) | TSHRFAAHTHRBPOLBAPEX1 | |
| SCHEMBL9279514 | 0.82 | TSHR (0.69) | TSHRFAAHTHRBPOLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994001511-A1 | PRESSURISED AEROSOL FORMULATION | SMITHKLINE BEECHAM PLC (GB) | 1994-01-20 | — | — | WO | disclosed |