Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.35 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.34 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.34 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.34 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5278870 | 0.89 | ALDH1A1 (0.40) | CYP19A1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL5280172 | 0.89 | GRIA4 (0.39) | CYP19A1GRIA4ALDH1A1MAPK1HPGD | |
| SCHEMBL5278982 | 0.86 | SLC9A1 (0.39) | CYP19A1GRIA4ALDH1A1MAPK1HPGD | |
| SCHEMBL5277421 | 0.85 | ALDH1A1 (0.33) | GRIA1GRIA2GRIA3GRIA4ALDH1A1 | |
| SCHEMBL5280676 | 0.83 | SLC9A1 (0.42) | CYP19A1ALDH1A1MAPK1SLC9A1 | |
| SCHEMBL5276068 | 0.82 | GRIA1 (0.36) | GRIA1GRIA2GRIA3GRIA4ALDH1A1 | |
| SCHEMBL5280369 | 0.79 | MAOB (0.35) | CYP19A1ALDH1A1MAPK1 | |
| SCHEMBL5275824 | 0.79 | ALDH1A1 (0.40) | CYP19A1GRIA4ALDH1A1MAPK1HPGD | |
| SCHEMBL5274771 | 0.79 | ALDH1A1 (0.30) | ALDH1A1HPGDTDP1 | |
| SCHEMBL5274892 | 0.79 | ALDH1A1 (0.40) | CYP19A1GRIA4ALDH1A1MAPK1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1859781-A2 | Brightening and/or colouring agent with triazoles | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-11-28 | — | — | EP | disclosed |