Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SCN4A | P35499 | 1/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 2/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5969695 | 0.77 | KDM4E (0.32) | ALDH1A1MAPTKDM4EMEN1CYP3A4 | |
| SCHEMBL3765842 | 0.71 | LMNA (0.49) | ALDH1A1MAPTKDM4EMEN1CYP3A4 | |
| SCHEMBL3015876 | 0.64 | MAOA (0.37) | ALDH1A1KDM4EKMT2ACES1BCHE | |
| SCHEMBL7329883 | 0.63 | MAPT (0.41) | ALDH1A1MAPTKDM4EMEN1CYP3A4 | |
| SCHEMBL10977545 | 0.63 | KDM4E (0.33) | ALDH1A1KDM4EMEN1KMT2AACHE | |
| SCHEMBL212380 | 0.60 | LMNA (0.38) | ALDH1A1MAPTKDM4EMEN1CYP3A4 | |
| SCHEMBL3266678 | 0.60 | MEN1 (0.41) | ALDH1A1MAPTKDM4EMEN1CYP3A4 | |
| SCHEMBL3691734 | 0.60 | LMNA (0.55) | LMNATSHRMAPK1SCN4ASCN5A | |
| SCHEMBL9435710 | 0.59 | GSK3A (0.42) | ALDH1A1MAPTKDM4EMEN1BLM | |
| SCHEMBL31495947 | 0.59 | GSK3A (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070264358-A1 | Methods and Compositions for Treating Mood Disorder | MOOD MANAGEMENT SCIENCES, INC. | 2007-11-15 | — | — | US | disclosed |
| WO-2007007182-A2 | SOLID AND LIQUID DOSAGE FORMS OF AN ANTIEPILEPTIC AGENT | AUROBINDO PHARMA LIMITED (IN) | 2007-01-18 | — | — | WO | disclosed |
| EP-1729737-A1 | DISINTEGRATING TABLETS COMPRISING LICARBAZEPINE | Novartis AG (CH) | 2006-12-13 | — | — | EP | disclosed |
| US-20060111343-A1 | Oxcarbazepine dosage forms | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2006-05-25 | — | — | US | disclosed |
| WO-2005092290-A1 | DISINTEGRATING TABLETS COMPRISING LICARBAZEPINE | NOVARTIS AG (CH) | 2005-10-06 | — | — | WO | disclosed |
| EP-1528927-A1 | USE OF CARBOXAMIDES FOR THE TREATMENT OF TINNITUS | Novartis AG (CH) | 2005-05-11 | — | — | EP | disclosed |
| EP-1513816-A2 | METHOD OF PREPARING A 5H-DIBENZ(B,F)AZEPINE-5-CARBOXAMIDE | TARO PHARMACEUTICALS U.S.A., INC. (US) | 2005-03-16 | — | — | EP | disclosed |
| WO-2004014391-A1 | USE OF CARBOXAMIDES FOR THE TREATMENT OF TINNITUS | NOVARTIS AG (CH) | 2004-02-19 | — | — | WO | disclosed |
| WO-2003106414-A2 | METHOD OF PREPARING A 5H-DIBENZ[B,F]AZEPINE-5-CARBOXAMIDE | TARO PHARMACEUTICALS U.S.A., INC. (US) | 2003-12-24 | — | — | WO | disclosed |
| US-4559174-A | NITRATION, REDUCTION AND HYDROLYSIS OF 5-CYANO5H-DIBENZ/B,FLAZEPINE | CIBA GEIGY CORPORATION (US) | 1985-12-17 | — | — | US | disclosed |
| US-4452738-A | Process for the manufacture of 5-carbamoyl-10-oxo-10,11-dihydro-5H-dibenz[b,]azepine | CIBA-GEIGY CORPORATION (US) | 1984-06-05 | — | — | US | disclosed |