Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | HPGD | P15428 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | HTT | P42858 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 11/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 5/20 | 0.57 |
| ▸ | CNR1 | P21554 | 1/20 | 0.55 |
| ▸ | CNR2 | P34972 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | PTGES | O14684 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL529003 | 0.93 | MAPT (0.66) | ALDH1A1HPGDSMN1; SMN2HTTMAPT | |
| SCHEMBL527884 | 0.92 | MAPT (0.74) | ALDH1A1HPGDSMN1; SMN2HTTMAPT | |
| SCHEMBL528499 | 0.91 | MAPT (0.63) | ALDH1A1HPGDSMN1; SMN2HTTMAPT | |
| SCHEMBL531055 | 0.90 | MAPT (0.71) | ALDH1A1HPGDSMN1; SMN2HTTMAPT | |
| SCHEMBL528041 | 0.90 | HTT (0.56) | ALDH1A1HPGDSMN1; SMN2HTTMAPT | |
| SCHEMBL528306 | 0.90 | KDM4E (0.67) | ALDH1A1HPGDSMN1; SMN2HTTMAPT | |
| SCHEMBL528901 | 0.89 | MAPT (0.74) | ALDH1A1HPGDSMN1; SMN2HTTMAPT | |
| SCHEMBL528969 | 0.88 | MAPT (0.60) | ALDH1A1HPGDSMN1; SMN2HTTMAPT | |
| SCHEMBL529297 | 0.87 | MAPT (0.59) | ALDH1A1HPGDSMN1; SMN2HTTMAPT | |
| SCHEMBL528307 | 0.87 | KMT2A (0.63) | ALDH1A1HPGDSMN1; SMN2HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014127-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | disclosed |