Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.74 |
| ▸ | LMNA | P02545 | 5/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | CNR1 | P21554 | 1/20 | 0.53 |
| ▸ | CNR2 | P34972 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL529003 | 0.91 | MAPT (0.66) | MAPTLMNAALDH1A1HPGDHTT | |
| SCHEMBL529032 | 0.91 | MAPT (0.77) | MAPTLMNAALDH1A1HPGDHTT | |
| SCHEMBL527884 | 0.91 | MAPT (0.74) | MAPTLMNAALDH1A1HPGDHTT | |
| SCHEMBL528293 | 0.89 | MAPT (0.59) | MAPTLMNAALDH1A1HPGDHTT | |
| SCHEMBL531055 | 0.89 | MAPT (0.71) | MAPTLMNAALDH1A1HPGDHTT | |
| SCHEMBL528227 | 0.89 | ALDH1A1 (0.64) | MAPTLMNAALDH1A1HPGDHTT | |
| SCHEMBL529428 | 0.88 | MAPT (0.57) | MAPTLMNAALDH1A1HPGDHTT | |
| SCHEMBL528800 | 0.88 | MAPT (0.62) | MAPTLMNAALDH1A1HPGDHTT | |
| SCHEMBL528007 | 0.88 | MAPT (0.62) | MAPTLMNAALDH1A1HPGDHTT | |
| SCHEMBL527918 | 0.87 | HPGD (0.65) | MAPTLMNAALDH1A1HPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014127-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | disclosed |