Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | CNR1 | P21554 | 1/20 | 0.52 |
| ▸ | CNR2 | P34972 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 7/20 | 0.52 |
| ▸ | GPR27 | Q9NS67 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL529297 | 0.94 | MAPT (0.59) | HTTALDH1A1HPGDSMN1; SMN2CNR1 | |
| SCHEMBL528702 | 0.90 | MAPT (0.58) | HTTALDH1A1HPGDSMN1; SMN2CNR1 | |
| SCHEMBL529639 | 0.90 | MAPT (0.55) | HTTALDH1A1HPGDSMN1; SMN2CNR1 | |
| SCHEMBL528227 | 0.90 | ALDH1A1 (0.64) | HTTALDH1A1HPGDSMN1; SMN2CNR1 | |
| SCHEMBL528499 | 0.88 | MAPT (0.63) | HTTALDH1A1HPGDSMN1; SMN2CNR1 | |
| SCHEMBL529590 | 0.87 | LMNA (0.49) | HTTALDH1A1HPGDSMN1; SMN2MAPT | |
| SCHEMBL528626 | 0.86 | ALDH1A1 (0.46) | HTTALDH1A1HPGDSMN1; SMN2CNR1 | |
| SCHEMBL529003 | 0.86 | MAPT (0.66) | HTTALDH1A1HPGDSMN1; SMN2MAPT | |
| SCHEMBL529051 | 0.86 | MAPT (0.71) | HTTALDH1A1HPGDSMN1; SMN2CNR1 | |
| SCHEMBL528323 | 0.85 | GAA (0.44) | HTTALDH1A1HPGDSMN1; SMN2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014127-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | disclosed |