SCHEMBL5282310

SCHEMBL5282310

CCCC=C(CC(=O)O)C(N)=O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 2/20 0.46
GRIK2 Q13002 1/20 0.46
CPB1 P15086 1/20 0.46
KDM4E B2RXH2 1/20 0.35
TSHR P16473 1/20 0.35
FFAR3 O14843 2/20 0.32
HDAC3 O15379 1/20 0.32
HDAC1 Q13547 1/20 0.32
HDAC2 Q92769 1/20 0.32
HDAC8 Q9BY41 1/20 0.32
LDHA P00338 1/20 0.32
SRR Q9GZT4 1/20 0.32
FAAH O00519 2/20 0.32
RECQL P46063 2/20 0.32
BACE1 P56817 1/20 0.32
EP300 Q09472 1/20 0.31
GMNN O75496 1/20 0.31
USP2 O75604 1/20 0.31
LMNA P02545 1/20 0.31
CYP1A2 P05177 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5288753 0.88 GRIK1 (0.49) GRIK1GRIK2CPB1FAAHRECQL
SCHEMBL6380794 0.83 GRIK1 (0.53) GRIK1GRIK2CPB1KDM4ETSHR
SCHEMBL205304 0.83 GRIK1 (0.53) GRIK1GRIK2CPB1KDM4ETSHR
SCHEMBL6370035 0.80 GRIK1 (0.46) GRIK1GRIK2KDM4EFAAHBACE1
SCHEMBL6370039 0.80 GRIK1 (0.46) GRIK1GRIK2KDM4EFAAHBACE1
SCHEMBL8216861 0.80 GRIK1 (0.46) GRIK1GRIK2KDM4EFAAHBACE1
Dimethylamine SCHEMBL27587558 0.79 GRIK1 (0.42) GRIK1GRIK2CPB1FAAHBACE1
SCHEMBL541990 0.78 GRIK1 (0.44) GRIK1GRIK2KDM4ETSHRFFAR3
SCHEMBL570952 0.78 GRIK1 (0.44) GRIK1GRIK2KDM4ETSHRFFAR3
SCHEMBL9751768 0.76 CPB1 (0.46) CPB1KDM4ETSHRLDHASRR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1281516-B1 Planographic printing plate precursor FUJIFILM CORP (JP) 2007-12-19 EP disclosed
US-6951171-B2 Using graft polymer on etched or anodized aluminum substrate FUJI PHOTO FILM CO., LTD. (JP) 2005-10-04 US disclosed
US-20030129520-A1 Using graft polymer on etched or anodized aluminum substrate FUJIFILM CORPORATION (JP) 2003-07-10 US disclosed
EP-1281516-A2 Planographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2003-02-05 EP disclosed