SCHEMBL5282316

SCHEMBL5282316

ClCCCOC(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 1/20 0.59
HRH4 Q9H3N8 1/20 0.49
TK2 O00142 11/20 0.43
TK1 P04183 1/20 0.42
DUT P33316 1/20 0.40
KCNA3 P22001 1/20 0.38
TSHR P16473 2/20 0.36
CYP2C9 P11712 1/20 0.36
ALOX15 P16050 1/20 0.36
CYP2C19 P33261 1/20 0.36
SLC6A1 P30531 1/20 0.36
CHRM2 P08172 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9637348 0.92 KIF11 (0.55) KIF11HRH4TK2TK1DUT
SCHEMBL3573169 0.87 KIF11 (0.63) KIF11HRH4TK2TK1DUT
SCHEMBL11275984 0.82 KIF11 (0.74) KIF11HRH4TK2TK1DUT
SCHEMBL4653330 0.80 KIF11 (0.60) KIF11HRH4TK2TK1DUT
SCHEMBL14578023 0.80 KIF11 (0.55) KIF11HRH4TK2TK1DUT
SCHEMBL2489713 0.79 KIF11 (0.59) KIF11HRH4TK2TK1DUT
SCHEMBL8389233 0.79 KIF11 (0.59) KIF11HRH4TK2TK1DUT
SCHEMBL913478 0.79 KIF11 (0.59) KIF11HRH4TK2TK1DUT
SCHEMBL2494600 0.79 KIF11 (0.77) KIF11HRH4TK2TK1DUT
SCHEMBL3398385 0.79 KIF11 (0.59) KIF11HRH4TK2TK1DUT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5565526-A Functionalized initiators for anionic polymerization FMC CORPORATION (US) 1996-10-15 US claimed
EP-0827423-B1 FUNCTIONALIZED CHAIN EXTENDED INITIATORS FOR ANIONIC POLYMERIZATION FMC CORP (US) 2007-12-12 EP disclosed
US-6858679-B2 Compositions providing improved functionalization of terminal anions and processes for improved functionalization of terminal anions FMC CORPORATION (US) 2005-02-22 US disclosed
US-6703446-B2 POLYMERS HAVING DIFFERENT FUNCTIONALITIES AT OPPOSITE ENDS OF THE POLYMER CHAIN; CAN BE COPOLYMERIZED WITH OTHER MONOMERS TO PROVIDE NOVEL COPOLYMERS POSSESSING A WIDE RANGE OF PHYSICAL PROPERTIES FMC CORPORATION, LITHIUM DIVISION 2004-03-09 US disclosed
US-6699939-B2 POLYMERS HAVING DIFFERENT FUNCTIONALITIES AT OPPOSITE ENDS OF THE POLYMER CHAIN; CAN BE COPOLYMERIZED WITH OTHER MONOMERS TO PROVIDE NOVEL COPOLYMERS POSSESSING A WIDE RANGE OF PHYSICAL PROPERTIES FMC CORPORATION, LITHIUM DIVISION 2004-03-02 US disclosed
EP-1028982-B1 COMPOSITIONS PROVIDING IMPROVED FUNCTIONALIZATION OF TERMINAL ANIONS AND PROCESSES FOR IMPROVED FUNCTIONALIZATION OF TERMINAL ANIONS FMC CORP (US) 2003-10-29 EP disclosed
US-20030153693-A1 Compositions providing improved functionalization of terminal anions and processes for improved functionalization of terminal anions QUIRK RODERIC PAUL (US) 2003-08-14 US disclosed
US-6605564-B1 Anionic polymerization initiators and salt additives selected from sodium chloride, sodium iodide, potassium chloride, potassium t-butoxide, for increasing the efficiency of reactions between living polymer anions and electrophiles FMC CORPORATION 2003-08-12 US disclosed
EP-0842206-B1 FUNCTIONAL TELECHELIC STAR POLYMERS FMC CORP (US) 2003-04-16 EP disclosed
US-6545103-B2 Living polymers FMC CORPORATION 2003-04-08 US disclosed
WO-1997005180-A1 FUNCTIONAL TELECHELIC STAR POLYMERS FMC CORPORATION (US) 1997-02-13 WO disclosed
WO-1997005174-A1 HETERO-TELECHELIC POLYMERS AND PROCESSES FOR MAKING SAME FMC CORPORATION (US) 1997-02-13 WO disclosed
WO-1997005176-A1 DEPROTECTION OF PROTECTED FUNCTIONAL POLYMERS FMC CORPORATION (US) 1997-02-13 WO disclosed
WO-1997005173-A1 METHACRYLATE AND ACRYLATE POLYMERS AND PROCESSES FOR MAKING SAME FMC CORPORATION (US) 1997-02-13 WO disclosed
US-5600021-A ORGANOMETALLIC COMPOUND CONTAINING ETHER GROUP FMC CORPORATION (US) 1997-02-04 US disclosed
EP-0746572-A1 NEW FUNCTIONALIZED INITIATORS FOR ANIONIC POLYMERIZATION FMC CORPORATION (US) 1996-12-11 EP disclosed
WO-1996035509-A1 FUNCTIONALIZED CHAIN EXTENDED INITIATORS FOR ANIONIC POLYMERIZATION FMC CORPORATION (US) 1996-11-14 WO disclosed
US-5567774-A USING SODIUM, POTASSIUM, OR LITHIUM HYDROCARBYL ETHER COMPOUNDS AS INITIATORS FMC CORPORATION (US) 1996-10-22 US disclosed
US-5565526-A Functionalized initiators for anionic polymerization FMC CORPORATION (US) 1996-10-15 US disclosed
WO-1995022566-A1 NEW FUNCTIONALIZED INITIATORS FOR ANIONIC POLYMERIZATION FMC CORPORATION (US) 1995-08-24 WO disclosed