Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydroxyguanidine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydroxyguanidine SCHEMBL28133728 | 0.97 | CA2 (0.42) | — | |
| Hydroxyguanidine SCHEMBL28226888 | 0.97 | CA2 (0.42) | — | |
| Hydroxyguanidine SCHEMBL28201789 | 0.97 | CA2 (0.42) | — | |
| Acetic Acid SCHEMBL28088245 | 0.88 | CA2 (0.44) | — | |
| Lactic Acid SCHEMBL28876414 | 0.85 | TP53 (0.50) | — | |
| Biguanide SCHEMBL28833765 | 0.81 | FFAR3 (0.44) | — | |
| Pimagedine SCHEMBL1065359 | 0.81 | — | — | |
| Acetic Acid SCHEMBL19458352 | 0.81 | FFAR3 (0.44) | — | |
| Acetic Acid SCHEMBL30784964 | 0.81 | FFAR3 (0.44) | — | |
| Biguanide SCHEMBL28444535 | 0.81 | FFAR3 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 128 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110511205-A | A kind of preparation method of high-purity glycolide | SHANDONG GUYUCHUN BIO TECH CO LTD | 2019-11-29 | — | — | CN | claimed |
| CN-110184043-A | Instant no residue modified cellulose fracturing fluid of one kind and preparation method thereof | 吉林省荣普达石油技术有限公司 | 2019-08-30 | — | — | CN | claimed |
| CN-109457309-A | A kind of polyglycolic acid oriented nanofibers beam and preparation method thereof | 中国科学院宁波材料技术与工程研究所 | 2019-03-12 | — | — | CN | claimed |
| CN-109364710-A | A kind of cleaning agent applied to desulfurizing tower doctor solution | 金澳科技（湖北）化工有限公司 | 2019-02-22 | — | — | CN | claimed |
| CN-106810620-B | A kind of gingko episperm pectin extraction method | 中国科学院大连化学物理研究所 | 2019-02-01 | — | — | CN | claimed |
| CN-106810619-B | A kind of gingko episperm pectin and polypentenol extracting method | 中国科学院大连化学物理研究所 | 2019-01-15 | — | — | CN | claimed |
| CN-106832045-B | A kind of method that gingko episperm extracts pectin and phenolic acid compound simultaneously | 中国科学院大连化学物理研究所 | 2018-12-14 | — | — | CN | claimed |
| CN-108793171-A | Preparation method of liquid silicon dioxide shadow eliminating material base liquid | 深圳飞世尔新材料股份有限公司 | 2018-11-13 | — | — | CN | claimed |
| CN-108753401-A | A kind of cotton stalk biomass fuel | 安徽大地节能科技有限公司 | 2018-11-06 | — | — | CN | claimed |
| CN-108707225-A | The method of polycarbonate synthesis in the presence of bimetallic catalyst and chain-transferring agent | 英佩雷尔创新有限公司 | 2018-10-26 | — | — | CN | claimed |
| CN-108102324-A | A kind of medical high polymer new material and its application | 谢涛 | 2018-06-01 | — | — | CN | claimed |
| CN-107759582-A | A kind of preparation method of new central skeletal muscle relaxant | 四川科瑞德制药股份有限公司 | 2018-03-06 | — | — | CN | claimed |
| CN-107647199-A | A kind of plum whitefish nurturing period anti-oxidant disease-resistant feed | 明光市皖淮水产养殖专业合作社 | 2018-02-02 | — | — | CN | claimed |
| CN-107574497-A | A kind of electrostatic spinning fiber is modified composite membrane and preparation method thereof | 华南理工大学 | 2018-01-12 | — | — | CN | claimed |
| CN-107440817-A | A kind of carotid artery flow controls support | 北京赛铂医药科技有限公司 | 2017-12-08 | — | — | CN | claimed |
| CN-107349038-A | A kind of preparation method of vivo inserted support | 山东省药学科学院 | 2017-11-17 | — | — | CN | claimed |
| CN-105026458-B | The method for purifying polyester | 益普生制药股份有限公司 | 2017-06-16 | — | — | CN | claimed |
| CN-104208753-B | Nanometer composite material capable of achieving tracing and controlled degradation in vivo and preparation method thereof | 中国科学院长春应用化学研究所 | 2017-02-22 | — | — | CN | claimed |
| CN-106186175-A | A kind of method of the photochemical degradating of phosphorus-containing wastewater | 宁波桑尼新材料科技有限公司 | 2016-12-07 | — | — | CN | claimed |
| CN-103429661-B | Biodegradable resin composition and molded body thereof | 三井化学株式会社 | 2016-11-16 | — | — | CN | claimed |