SCHEMBL5282811

SCHEMBL5282811

CCOC(=O)[C]1C=CC=CN1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 5/20 0.43
CA2 P00918 5/20 0.43
CA12 O43570 4/20 0.43
CA7 P43166 4/20 0.43
CA9 Q16790 4/20 0.43
CA14 Q9ULX7 4/20 0.43
ESR1 P03372 1/20 0.43
ESR2 Q92731 1/20 0.43
CYP1A2 P05177 3/20 0.42
LMNA P02545 2/20 0.42
CYP3A4 P08684 1/20 0.42
MAOA P21397 1/20 0.42
TSHR P16473 2/20 0.41
RAB9A P51151 1/20 0.40
POLB P06746 1/20 0.40
GAA P10253 1/20 0.40
HPGD P15428 3/20 0.39
RECQL P46063 1/20 0.39
ALDH1A1 P00352 1/20 0.39
HSP90AA1 P07900 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6202699 0.78 PHLPP2 (0.49) CYP1A2LMNAMAOARAB9APOLB
SCHEMBL27625055 0.77 CA1 (0.40) CA1CA2CA12CA7CA9
SCHEMBL6197059 0.76 KMT2A (0.41) CA1CA2CA12CA7CA9
SCHEMBL7141933 0.73 CA1 (0.42) CA1CA2CA12CA7CA9
SCHEMBL3977539 0.71 TSHR (0.39) CA1CA2CA12CA7CA9
Hydrochloric Acid SCHEMBL27772092 0.71 CA1 (0.41) CA1CA2CA12CA7CA9
SCHEMBL28833900 0.71 ADORA3 (0.43) CA1CA2CA12CA7CA9
SCHEMBL5583457 0.70 CYP1A2 (0.39) CA1CA2CA12CA7CA9
SCHEMBL35206 0.69
SCHEMBL10376455 0.68 ALDH1A1 (0.40) LMNARAB9AGAAALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1168066-B1 Silver salt photothermographic dry imaging material KONICA CORP (JP) 2007-12-05 EP disclosed
EP-1199596-B1 Silver salt photothermographic material KONICA CORP (JP) 2006-09-20 EP disclosed
EP-1130017-B1 Azole derivatives and their use as superoxide radical inhibitors OTSUKA PHARMA CO LTD (JP) 2005-06-15 EP disclosed
EP-1035430-B1 Silver halide photographic material KONISHIROKU PHOTO IND (JP) 2005-01-05 EP disclosed
EP-1033618-B1 Thermally developable photosensitive material KONISHIROKU PHOTO IND (JP) 2004-11-03 EP disclosed
US-6709809-B2 LIGHT SENSITIVE LAYER; STORAGE STABILITY KONICA CORPORATION (JP) 2004-03-23 US disclosed
US-6677113-B2 INFRARED-SENSITIVE SILVER HALIDE EMULSION EXHIBITING A HIGH SENSITIVITY, A LOW FOG AND REDUCED VARIATION IN SENSITIVITY FOLLOWING STORAGE KONICA CORPORATION (JP) 2004-01-13 US disclosed
US-20030143499-A1 Sensitizing dye and silver halide photographic material KAGAWA NOBUAKI (JP) 2003-07-31 US disclosed
US-6558896-B2 Used in the field of lithographic printing plates or medical treatment KONICA CORPORATION (JP) 2003-05-06 US disclosed
US-6489091-B2 PHOTOSENSITIVE LAYER CONTAINING ORGANIC SILVER SALT, SILVER HALIDE EMULSION AND SOLVENT ON SUPPORT KONICA CORPORATION (JP) 2002-12-03 US disclosed
US-6265146-B1 SUPPORT HAVING THEREON AN ORGANIC SILVER SALT, A BINDER, A PHOTOSENSITIVE SILVER HALIDE, AN INFRARED-SENSITIZING DYE AND A HETEROATOM CONTAINING MACROCYCLIC COMPOUND. KONICA CORPORATION (JP) 2001-07-24 US disclosed
EP-1035430-A2 Sensitizing dye and silver halide photographic material KONICA CORPORATION (JP) 2000-09-13 EP disclosed
EP-1033618-A1 Thermally developable photosensitive material KONICA CORPORATION (JP) 2000-09-06 EP disclosed
US-6080764-A PROTECTING VARIOUS TISSUE CELLS FROM DISTURBANCES ASSOCIATED WITH ISCHEMIA AND BLOOD REPERFUSION IN HEART, BRAIN, KIDNEY, LUNG AND DIGESTIVE TRACT BY INHIBITING SUPEROXIDE-RELEASE BY NEUTROPHILIC LEUKOCYTES OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2000-06-27 US disclosed
EP-0934937-A1 Azole derivatives as superoxide radical inhibitor OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1999-08-11 EP disclosed
US-5677319-A THIAZOLE DERIVATIVE OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1997-10-14 US disclosed
US-5643932-A PREVENTS CELL DAMAGE AFTER ISCHEMIA AND RE-PERFUSION, SUBSTITUTED THIAZOLES OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1997-07-01 US disclosed
US-5639770-A SUPEROXIDE INHIBITOR OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1997-06-17 US disclosed
EP-0600092-A1 THIAZOLE DERIVATIVE OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1994-06-08 EP disclosed
EP-0513387-A1 ACTIVE OXYGEN INHIBITOR OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1992-11-19 EP disclosed