Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | TOP2A | P11388 | 1/20 | 0.38 |
| ▸ | SLC9A1 | P19634 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5279019 | 0.94 | SLC9A1 (0.40) | GRM2TOP2ASLC9A1ALDH1A1ATM | |
| SCHEMBL5279006 | 0.90 | GRM2 (0.37) | GRM2TOP2ASLC9A1ALDH1A1KMT2A | |
| SCHEMBL5276783 | 0.83 | MAPT (0.35) | GRM2TOP2ASLC9A1ALDH1A1KMT2A | |
| SCHEMBL5286658 | 0.82 | SLC9A1 (0.38) | GRM2TOP2ASLC9A1ALDH1A1ATM | |
| SCHEMBL5276240 | 0.82 | ALDH1A1 (0.41) | GRM2TOP2ASLC9A1ALDH1A1ATM | |
| SCHEMBL5276739 | 0.81 | SLC9A1 (0.37) | GRM2TOP2ASLC9A1ALDH1A1ATM | |
| SCHEMBL5280835 | 0.81 | SLC9A1 (0.41) | GRM2TOP2ASLC9A1ALDH1A1ATM | |
| SCHEMBL5274531 | 0.81 | SLC9A1 (0.37) | GRM2TOP2ASLC9A1ALDH1A1ATM | |
| SCHEMBL5281679 | 0.79 | SLC9A1 (0.36) | GRM2TOP2ASLC9A1ALDH1A1ATM | |
| SCHEMBL5275423 | 0.79 | SLC9A1 (0.36) | GRM2TOP2ASLC9A1ALDH1A1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1859781-A2 | Brightening and/or colouring agent with triazoles | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-11-28 | — | — | EP | disclosed |