Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 9/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | DRD4 | P21917 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6037916 | 0.88 | GFER (0.55) | GFERALDH1A1MAPTMAPK1L3MBTL1 | |
| SCHEMBL6038084 | 0.86 | GFER (0.58) | GFERALDH1A1MAPTL3MBTL1KMT2A | |
| SCHEMBL1378043 | 0.83 | HDAC1 (0.72) | GFERALDH1A1MAPTMAPK1L3MBTL1 | |
| SCHEMBL5281130 | 0.83 | MAPT (0.61) | GFERALDH1A1MAPTMAPK1L3MBTL1 | |
| SCHEMBL1374155 | 0.82 | ALDH1A1 (0.59) | GFERALDH1A1MAPTMAPK1L3MBTL1 | |
| SCHEMBL6038021 | 0.80 | MAPT (0.57) | GFERALDH1A1MAPTL3MBTL1KMT2A | |
| SCHEMBL6037984 | 0.80 | MAPT (0.57) | GFERALDH1A1MAPTL3MBTL1KMT2A | |
| SCHEMBL6038357 | 0.80 | L3MBTL1 (0.58) | GFERALDH1A1MAPTL3MBTL1KMT2A | |
| SCHEMBL8325536 | 0.79 | MAPT (0.68) | GFERALDH1A1MAPTMAPK1L3MBTL1 | |
| SCHEMBL9987782 | 0.77 | MAPT (0.67) | GFERALDH1A1MAPTMAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1863804-A1 | INHIBITORS OF HISTONE DEACETYLASE | Methylgene, Inc. (CA) | 2007-12-12 | — | — | EP | disclosed |
| WO-2006102760-A1 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE INC. (CA) | 2006-10-05 | — | — | WO | disclosed |