Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | GPR174 | Q9BXC1 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5294909 | 0.90 | ALDH1A1 (0.40) | MAPTALDH1A1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL5281743 | 0.84 | ALDH1A1 (0.38) | MAPTALDH1A1LMNAKMT2APOLB | |
| SCHEMBL6491940 | 0.78 | MAPT (0.48) | MAPTALDH1A1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL5284741 | 0.78 | ACACB (0.37) | ACACB | |
| SCHEMBL4705323 | 0.77 | ALDH1A1 (0.41) | MAPTALDH1A1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL240096 | 0.77 | MAPT (0.43) | MAPTALDH1A1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL4703887 | 0.76 | ALDH1A1 (0.40) | MAPTALDH1A1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL6211391 | 0.76 | ALDH1A1 (0.40) | MAPTALDH1A1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL30890308 | 0.75 | HTT (0.53) | MAPTALDH1A1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL31640059 | 0.75 | HTT (0.53) | MAPTALDH1A1LMNAKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007004049-A1 | OXAZOLIDINONES CONTAINING AZETIDINE AS ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2007-01-11 | — | — | WO | disclosed |